L2L L2L Microarray Analysis Tool

Probes from R06AX.profile.d50 that match tricarboxylic acid cycle

Results summary View all lists in GO:BiolProc View all genes in R06AX.profile.d50

tricarboxylic acid cycle

A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two C02 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

enrichment: 22.47-fold
p-value: 3.64e-03

image image
Probe ID Name G T D X E P R C S image image Description
213333_AT MDH2         E         image image malate dehydrogenase 2, NAD (mitochondrial)
210045_AT IDH2         E         image image isocitrate dehydrogenase 2 (NADP+), mitochondrial