L2L L2L Microarray Analysis Tool

Results for R06AX.profile.d50

Results summary View all lists in GO:BiolProc View all genes in R06AX.profile.d50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
tRNA metabolic process The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. 100 0.25 5 20.23 5.72e-06
DNA replication The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. 277 0.68 6 8.76 7.66e-05
acetyl-CoA metabolic process The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. 44 0.11 3 27.58 1.85e-04
carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). 679 1.68 8 4.77 3.48e-04
organic acid metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. 681 1.68 8 4.75 3.54e-04
tRNA aminoacylation for protein translation The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis. 56 0.14 3 21.67 3.80e-04
amino acid activation The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. 56 0.14 3 21.67 3.80e-04
tRNA aminoacylation The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. 56 0.14 3 21.67 3.80e-04
DNA-dependent DNA replication The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. 140 0.35 4 11.56 4.38e-04
coenzyme metabolic process The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. 201 0.50 4 8.05 1.67e-03
mismatch repair A system for the correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. 34 0.08 2 23.80 3.25e-03
maintenance of fidelity during DNA-dependent DNA replication The correction of errors made during DNA replication by either intrinsic DNA polymerase proofreading activity or via mismatch repair. 35 0.09 2 23.12 3.44e-03
cofactor metabolic process The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. 247 0.61 4 6.55 3.51e-03
tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two C02 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. 36 0.09 2 22.47 3.64e-03
acetyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated. 36 0.09 2 22.47 3.64e-03
energy derivation by oxidation of organic compounds 127 0.31 3 9.56 4.01e-03
coenzyme catabolic process The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. 38 0.09 2 21.29 4.05e-03
base-excision repair In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. 41 0.10 2 19.73 4.70e-03
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. 622 1.54 6 3.90 4.94e-03
DNA replication initiation The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action. 44 0.11 2 18.39 5.40e-03
cofactor catabolic process The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein. 47 0.12 2 17.21 6.14e-03
tRNA processing The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. 48 0.12 2 16.86 6.39e-03
aerobic respiration The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor. 49 0.12 2 16.51 6.65e-03
cellular respiration The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration). 55 0.14 2 14.71 8.32e-03
DNA metabolic process The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. 922 2.28 7 3.07 8.85e-03

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