L2L L2L Microarray Analysis Tool

Probes from D01AC.profile.d50 that match senescence_rep-ind_dn

Results summary View all lists in L2L MDB View all genes in D01AC.profile.d50

senescence_rep-ind_dn

Down-regulated in models of both replicative (high-passge human foreskin fibroblast) and induced (repression of E7 in HeLa) cellular senescence.

enrichment: 23.66-fold
p-value: 2.67e-11

 image image
Probe ID Name G T D X E P R C S image image Description
218350_S_AT GMNN G   D             image image geminin, DNA replication inhibitor
212141_AT MCM4 G           R     image image minichromosome maintenance complex component 4
220085_AT HELLS G   D       R     image image helicase, lymphoid-specific
221677_S_AT DONSON     D             image image downstream neighbor of SON
204603_AT EXO1 G     X           image image exonuclease 1
201890_AT RRM2 G                 image image ribonucleotide reductase M2 polypeptide
202532_S_AT DHFR                   image image dihydrofolate reductase
221521_S_AT GINS2 G                 image image GINS complex subunit 2 (Psf2 homolog)
212023_S_AT MKI67 G                 image image antigen identified by monoclonal antibody Ki-67
222037_AT MCM4 G           R     image image minichromosome maintenance complex component 4