L2L L2L Microarray Analysis Tool

Probes from D01A.profile.d50 that match senescence_hff_dn

Results summary View all lists in L2L MDB View all genes in D01A.profile.d50

senescence_hff_dn

Down-regulated in primary human foreskin fibroblasts at replicative senescence (passage 26) compared to active replication (passage 8).

enrichment: 14.88-fold
p-value: 3.90e-10

 image image
Probe ID Name G T D X E P R C S image image Description
204159_AT CDKN2C G                 image image cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
218350_S_AT GMNN G   D             image image geminin, DNA replication inhibitor
220085_AT HELLS G   D       R     image image helicase, lymphoid-specific
209891_AT SPC25                   image image SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
211998_AT H3F3B                   image image H3 histone, family 3B (H3.3B)
201890_AT RRM2 G                 image image ribonucleotide reductase M2 polypeptide
204444_AT KIF11   T               image image kinesin family member 11
212023_S_AT MKI67 G                 image image antigen identified by monoclonal antibody Ki-67
203213_AT CDC2 G     X   P       image image cell division cycle 2, G1 to S and G2 to M
213226_AT CCNA2       X     R     image image cyclin A2
202436_S_AT CYP1B1         E         image image cytochrome P450, family 1, subfamily B, polypeptide 1