L2L L2L Microarray Analysis Tool

Results for S02AA.profile.ud50

Results summary View all lists in L2L MDB View all genes in S02AA.profile.ud50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
preadip_vs_fibro_up Upregulated following 6hr differentiation of murine 3T3-L1 fibroblasts into preadipocytes; presumed direct transcriptional targets of differentiation cocktail of insulin, dexamethasone and isobutyl-methylxanthine 29 0.14 3 20.92 4.01e-04
pubertal_mammary_4-5wks_dn Down-regulated > 1.5-fold in the developing mouse mammary gland between 4 and 5 weeks of age. 283 1.40 7 5.00 5.91e-04
idx_tsa_up_cluster1 Strongly up-regulated at 2 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 1) 44 0.22 3 13.79 1.38e-03
stress_arsenic_specific_up Genes up-regulated 4 hours following arsenic treatment that discriminate arsenic from other stress agents 266 1.32 6 4.56 2.28e-03
fsh_rat_granulosa_up Up-regulated by FSH in immortalized rat granulosa cells (rFSH-17) 15 0.07 2 26.97 2.46e-03
ifnalpha_resist_dn Down-regulated in mycosis fungoides (cutaneous T-cell lymphoma) T-cells resistant to IFN-alpha, compared to sensitive parent cell line 25 0.12 2 16.18 6.80e-03
cox1_ko_cortex_up Up-regulated in the cerebral cortex of COX1-/- mice compared to wild-type controls. 80 0.40 3 7.59 7.48e-03
hypoxia_reg_up Upregulated by hypoxia in renal cells, and downregulated with reoxygenation 80 0.40 3 7.59 7.48e-03
metastasis_adenocarc_up Up-regulated in adenocarcinoma metastases, compared to similar primary tumors; predictive of metastatic potential 81 0.40 3 7.49 7.74e-03
alk5_hmvec_2hr_up Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). 347 1.72 6 3.50 8.16e-03
alk5_hmvec_4hr_up Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). 347 1.72 6 3.50 8.16e-03
cox2_ko_hippocampus_dn Down-regulated in the hippocampus of COX2-/- mice compared to wild-type controls. 84 0.42 3 7.22 8.55e-03
insulin_adip_sens_dn Down-regulated by insulin in murine adipocytes, but response is blunted following induction of insulin-resistance with TNFalpha treatment 29 0.14 2 13.95 9.08e-03
brca_prognosis_neg Genes whose expression is consistently negatively correlated with breast cancer outcomes - higher expression is associated with metastasis and poor prognosis 166 0.82 4 4.87 9.68e-03

Raw data (tab-delimited .txt)