L2L L2L Microarray Analysis Tool

Results for R03BA.profile.ud50

Results summary View all lists in GO:BiolProc View all genes in R03BA.profile.ud50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
regulation of interleukin-6 biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6. 8 0.04 3 75.85 6.64e-06
interleukin-6 production The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. 10 0.05 3 60.68 1.41e-05
interleukin-6 biosynthetic process The chemical reactions and pathways resulting in the formation of interleukin-6. 10 0.05 3 60.68 1.41e-05
positive regulation of interleukin-6 biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6. 7 0.03 2 57.79 5.05e-04
negative regulation of transport Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells. 33 0.16 3 18.39 5.90e-04
regulation of chemokine biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines. 8 0.04 2 50.57 6.71e-04
chemokine production The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. 9 0.04 2 44.95 8.60e-04
chemokine biosynthetic process The chemical reactions and pathways resulting in the formation of chemokines, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions. 9 0.04 2 44.95 8.60e-04
chemokine metabolic process The chemical reactions and pathways involving chemokines, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions. 9 0.04 2 44.95 8.60e-04
negative regulation of biological process Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. 1697 8.39 19 2.26 1.09e-03
acute-phase response Process involving non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals. 44 0.22 3 13.79 1.38e-03
thermoregulation A homeostatic process by which an organism modulates its internal body temperature. 12 0.06 2 33.71 1.56e-03
response to external stimulus A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. 759 3.75 11 2.93 1.70e-03
negative regulation of cellular process Any process that stops, prevents or reduces the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. 1642 8.12 18 2.22 1.81e-03
cytoplasmic sequestering of transcription factor The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. 13 0.06 2 31.12 1.84e-03
cytoplasmic sequestering of protein The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell. 13 0.06 2 31.12 1.84e-03
negative regulation of protein import into nucleus Any process that stops, prevents or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. 16 0.08 2 25.28 2.80e-03
negative regulation of transcription factor import into nucleus Any process that stops, prevents or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. 16 0.08 2 25.28 2.80e-03
negative regulation of nucleocytoplasmic transport Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus. 17 0.08 2 23.80 3.16e-03
negative regulation of protein transport Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells. 17 0.08 2 23.80 3.16e-03
heme biosynthetic process The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. 19 0.09 2 21.29 3.95e-03
porphyrin biosynthetic process The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. 21 0.10 2 19.26 4.82e-03
response to metal ion A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. 21 0.10 2 19.26 4.82e-03
tetrapyrrole biosynthetic process The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. 21 0.10 2 19.26 4.82e-03
regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells. 136 0.67 4 5.95 4.86e-03
cell death The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. 1152 5.70 13 2.28 5.76e-03
death A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. 1152 5.70 13 2.28 5.76e-03
neutrophil chemotaxis The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. 24 0.12 2 16.86 6.28e-03
cytokine production The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. 153 0.76 4 5.29 7.32e-03
response to wounding A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. 560 2.77 8 2.89 7.47e-03
response to inorganic substance A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. 27 0.13 2 14.98 7.90e-03
negative regulation of myeloid cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of myeloid cell differentiation. 27 0.13 2 14.98 7.90e-03
steroid hormone receptor signaling pathway Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor. 83 0.41 3 7.31 8.27e-03
heme metabolic process The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. 28 0.14 2 14.45 8.48e-03
apoptosis A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. 1078 5.33 12 2.25 8.59e-03
regulation of cytokine biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. 85 0.42 3 7.14 8.83e-03
programmed cell death Cell death resulting from activation of endogenous cellular processes. 1086 5.37 12 2.24 9.07e-03
embryo implantation Attachment of the blastocyst to the uterine lining. 29 0.14 2 13.95 9.08e-03
regulation of transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. 701 3.47 9 2.60 9.13e-03
regulation of cell proliferation Any process that modulates the frequency, rate or extent of cell proliferation. 704 3.48 9 2.59 9.37e-03
porphyrin metabolic process The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. 30 0.15 2 13.48 9.70e-03
tetrapyrrole metabolic process The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. 30 0.15 2 13.48 9.70e-03
intracellular receptor-mediated signaling pathway Any series of molecular signals initiated by a ligand entering the target cell, where it binds to an intracellular receptor. 88 0.44 3 6.90 9.70e-03

Raw data (tab-delimited .txt)