L2L Microarray Analysis Tool
Results for P02CA.profile.ud50
| Results summary | View all lists in GO:BiolProc | View all genes in P02CA.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| microtubule-based movement | Movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins. | 110 | 0.54 | 9 | 16.55 | 5.23e-09 |
| protein polymerization | The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. | 82 | 0.41 | 8 | 19.73 | 9.19e-09 |
| natural killer cell mediated immunity | The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines. | 18 | 0.09 | 5 | 56.19 | 2.40e-08 |
| natural killer cell mediated cytotoxicity | The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. | 18 | 0.09 | 5 | 56.19 | 2.40e-08 |
| cytoskeleton-dependent intracellular transport | The directed movement of substances along cytoskeletal elements such as microfilaments or microtubules within a cell. | 139 | 0.69 | 9 | 13.10 | 4.06e-08 |
| leukocyte mediated cytotoxicity | The directed killing of a target cell by a leukocyte. | 21 | 0.10 | 5 | 48.16 | 5.63e-08 |
| cell killing | Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. | 26 | 0.13 | 5 | 38.90 | 1.78e-07 |
| microtubule-based process | Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. | 237 | 1.17 | 10 | 8.53 | 4.01e-07 |
| cell motility | Any process involved in the controlled movement of a cell. | 622 | 3.08 | 13 | 4.23 | 1.93e-05 |
| localization of cell | The processes by which a cell is transported to, and/or maintained in, a specific location. | 622 | 3.08 | 13 | 4.23 | 1.93e-05 |
| lymphocyte mediated immunity | Any process involved in the carrying out of an immune response by a lymphocyte. | 116 | 0.57 | 6 | 10.46 | 2.72e-05 |
| leukocyte mediated immunity | Any process involved in the carrying out of an immune response by a leukocyte. | 124 | 0.61 | 6 | 9.79 | 3.96e-05 |
| immune effector process | Any process of the immune system that occurs as part of an immune response. | 143 | 0.71 | 6 | 8.49 | 8.75e-05 |
| innate immune response | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. | 97 | 0.48 | 5 | 10.43 | 1.30e-04 |
| cytoskeleton organization and biogenesis | A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. | 661 | 3.27 | 12 | 3.67 | 1.48e-04 |
| induction of apoptosis | A process that directly activates any of the steps required for cell death by apoptosis. | 341 | 1.69 | 8 | 4.75 | 3.49e-04 |
| induction of programmed cell death | A process which directly activates any of the steps required for programmed cell death. | 343 | 1.70 | 8 | 4.72 | 3.62e-04 |
| translational initiation | The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. | 79 | 0.39 | 4 | 10.24 | 6.68e-04 |
| positive regulation of apoptosis | Any process that activates or increases the frequency, rate or extent of cell death by apoptosis. | 396 | 1.96 | 8 | 4.09 | 9.21e-04 |
| positive regulation of programmed cell death | Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 400 | 1.98 | 8 | 4.05 | 9.82e-04 |
| cell development | The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. | 1692 | 8.37 | 19 | 2.27 | 1.05e-03 |
| regulation of smooth muscle cell proliferation | Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation. | 10 | 0.05 | 2 | 40.45 | 1.07e-03 |
| protein-RNA complex assembly | The aggregation and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. | 154 | 0.76 | 5 | 6.57 | 1.09e-03 |
| smooth muscle cell proliferation | The multiplication or reproduction of smooth muscle cells, resulting in the rapid expansion of a cell population. | 11 | 0.05 | 2 | 36.78 | 1.31e-03 |
| muscle cell proliferation | The rapid expansion of a muscle cell population by cell division. | 13 | 0.06 | 2 | 31.12 | 1.84e-03 |
| regulation of apoptosis | Any process that modulates the occurrence or rate of cell death by apoptosis. | 785 | 3.88 | 11 | 2.83 | 2.20e-03 |
| cell death | The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. | 1152 | 5.70 | 14 | 2.46 | 2.24e-03 |
| death | A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. | 1152 | 5.70 | 14 | 2.46 | 2.24e-03 |
| regulation of programmed cell death | Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 793 | 3.92 | 11 | 2.81 | 2.37e-03 |
| regulation of chemotaxis | Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. | 16 | 0.08 | 2 | 25.28 | 2.80e-03 |
| positive regulation of cell migration | Any process that activates or increases the frequency, rate or extent of cell migration. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| apoptosis | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. | 1078 | 5.33 | 13 | 2.44 | 3.36e-03 |
| programmed cell death | Cell death resulting from activation of endogenous cellular processes. | 1086 | 5.37 | 13 | 2.42 | 3.57e-03 |
| intracellular transport | The directed movement of substances within a cell. | 982 | 4.85 | 12 | 2.47 | 4.25e-03 |
| cell differentiation | The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate. | 2359 | 11.66 | 22 | 1.89 | 4.32e-03 |
| cellular developmental process | A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. | 2359 | 11.66 | 22 | 1.89 | 4.32e-03 |
| myofibril assembly | Formation of myofibrils, the repeating units of striated muscle. | 21 | 0.10 | 2 | 19.26 | 4.82e-03 |
| muscle cell development | The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. | 21 | 0.10 | 2 | 19.26 | 4.82e-03 |
| striated muscle cell development | The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. | 21 | 0.10 | 2 | 19.26 | 4.82e-03 |
| regulation of viral genome replication | Any process that modulates the frequency, rate or extent of viral genome replication. | 22 | 0.11 | 2 | 18.39 | 5.29e-03 |
| regulation of caspase activity | Any process that modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. | 75 | 0.37 | 3 | 8.09 | 6.26e-03 |
| neutrophil chemotaxis | The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. | 24 | 0.12 | 2 | 16.86 | 6.28e-03 |
| positive regulation of locomotion | Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. | 25 | 0.12 | 2 | 16.18 | 6.80e-03 |
| positive regulation of cell motility | Any process that activates or increases the frequency, rate or extent of the movement of a cell. | 25 | 0.12 | 2 | 16.18 | 6.80e-03 |
| establishment of cellular localization | The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell. | 1183 | 5.85 | 13 | 2.22 | 7.10e-03 |
| ribonucleoprotein complex biogenesis and assembly | The cellular process by which a complex containing RNA and proteins, is synthesized, aggregates, and bonds together. | 239 | 1.18 | 5 | 4.23 | 7.10e-03 |
| regulation of viral life cycle | Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts. | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |
| striated muscle cell differentiation | The process whereby a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle. | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |
| actomyosin structure organization and biogenesis | A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin. The myosin may be organized into filaments. | 27 | 0.13 | 2 | 14.98 | 7.90e-03 |
| cellular localization | The processes by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell. | 1214 | 6.00 | 13 | 2.17 | 8.68e-03 |
| skeletal muscle development | The process whose specific outcome is the progression of the skeletal muscle over time, from its formation to the mature structure. | 85 | 0.42 | 3 | 7.14 | 8.83e-03 |
| muscle development | The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. | 256 | 1.27 | 5 | 3.95 | 9.38e-03 |