L2L Microarray Analysis Tool

Results summary	View all lists in GO:BiolProc	View all genes in P02CA.profile.u50

List Name	Description	Total probes	Expected matches	Actual matches	Fold Enrichment	Binomial p-value
regulation of smooth muscle cell proliferation	Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.	10	0.02	2	80.91	2.71e-04
smooth muscle cell proliferation	The multiplication or reproduction of smooth muscle cells, resulting in the rapid expansion of a cell population.	11	0.03	2	73.55	3.31e-04
muscle cell proliferation	The rapid expansion of a muscle cell population by cell division.	13	0.03	2	62.24	4.68e-04
regulation of chemotaxis	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.	16	0.04	2	50.57	7.17e-04
positive regulation of cell migration	Any process that activates or increases the frequency, rate or extent of cell migration.	17	0.04	2	47.59	8.11e-04
cell motility	Any process involved in the controlled movement of a cell.	622	1.54	7	4.55	1.04e-03
localization of cell	The processes by which a cell is transported to, and/or maintained in, a specific location.	622	1.54	7	4.55	1.04e-03
myofibril assembly	Formation of myofibrils, the repeating units of striated muscle.	21	0.05	2	38.53	1.24e-03
muscle cell development	The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.	21	0.05	2	38.53	1.24e-03
striated muscle cell development	The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.	21	0.05	2	38.53	1.24e-03
regulation of viral genome replication	Any process that modulates the frequency, rate or extent of viral genome replication.	22	0.05	2	36.78	1.37e-03
neutrophil chemotaxis	The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.	24	0.06	2	33.71	1.63e-03
positive regulation of locomotion	Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.	25	0.06	2	32.36	1.77e-03
positive regulation of cell motility	Any process that activates or increases the frequency, rate or extent of the movement of a cell.	25	0.06	2	32.36	1.77e-03
regulation of viral life cycle	Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.	26	0.06	2	31.12	1.91e-03
striated muscle cell differentiation	The process whereby a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.	26	0.06	2	31.12	1.91e-03
actomyosin structure organization and biogenesis	A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin. The myosin may be organized into filaments.	27	0.07	2	29.97	2.06e-03
leukocyte chemotaxis	The movement of a leukocyte in response to an external stimulus.	32	0.08	2	25.28	2.88e-03
myoblast development	The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure.	32	0.08	2	25.28	2.88e-03
myoblast maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state.	32	0.08	2	25.28	2.88e-03
muscle development	The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.	256	0.63	4	6.32	3.98e-03
epidermal growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands.	38	0.09	2	21.29	4.05e-03
leukocyte migration	The movement of leukocytes within or between different tissues and organs of the body.	39	0.10	2	20.75	4.26e-03
cell cycle arrest	Any process by which progression through the cell cycle is halted during one of the normal phases (G1, S, G2, M).	135	0.33	3	8.99	4.75e-03
myeloid leukocyte activation	A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.	43	0.11	2	18.82	5.16e-03
mitosis	Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.	284	0.70	4	5.70	5.73e-03
calcium-mediated signaling	A series of molecular signals in which a cell uses calcium ions to convert an extracellular signal into a response.	47	0.12	2	17.21	6.14e-03
M phase of mitotic cell cycle	Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	290	0.72	4	5.58	6.16e-03
cytokine and chemokine mediated signaling pathway	Any series of molecular signals generated as a consequence of a cytokine or chemokine binding to a cell surface receptor.	50	0.12	2	16.18	6.92e-03
cell differentiation	The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.	2359	5.83	13	2.23	7.01e-03
cellular developmental process	A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.	2359	5.83	13	2.23	7.01e-03
leukocyte activation	A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.	305	0.75	4	5.31	7.33e-03
viral genome replication	Any process involved directly in viral genome replication, including viral nucleotide metabolism.	52	0.13	2	15.56	7.46e-03
myoblast differentiation	The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a cell type that gives rise to mature contractile cells called myocytes. Fusion of myoblasts gives rise to the myotubes that eventually develop into skeletal muscle fibers.	55	0.14	2	14.71	8.32e-03
B cell differentiation	The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a B cell.	57	0.14	2	14.19	8.91e-03
cell activation	A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.	330	0.82	4	4.90	9.59e-03
wound healing	The series of events that restore integrity to a damaged tissue, following an injury.	177	0.44	3	6.86	9.97e-03

regulation of smooth muscle cell proliferation

Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.

10

0.02

2

80.91

2.71e-04

smooth muscle cell proliferation

The multiplication or reproduction of smooth muscle cells, resulting in the rapid expansion of a cell population.

11

0.03

2

73.55

3.31e-04

muscle cell proliferation

The rapid expansion of a muscle cell population by cell division.

13

0.03

2

62.24

4.68e-04

regulation of chemotaxis

Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

16

0.04

2

50.57

7.17e-04

positive regulation of cell migration

Any process that activates or increases the frequency, rate or extent of cell migration.

17

0.04

2

47.59

8.11e-04

cell motility

Any process involved in the controlled movement of a cell.

622

1.54

7

4.55

1.04e-03

localization of cell

The processes by which a cell is transported to, and/or maintained in, a specific location.

622

1.54

7

4.55

1.04e-03

myofibril assembly

Formation of myofibrils, the repeating units of striated muscle.

21

0.05

2

38.53

1.24e-03

muscle cell development

The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.

21

0.05

2

38.53

1.24e-03

striated muscle cell development

The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.

21

0.05

2

38.53

1.24e-03

regulation of viral genome replication

Any process that modulates the frequency, rate or extent of viral genome replication.

22

0.05

2

36.78

1.37e-03

neutrophil chemotaxis

The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

24

0.06

2

33.71

1.63e-03

positive regulation of locomotion

Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.

25

0.06

2

32.36

1.77e-03

positive regulation of cell motility

Any process that activates or increases the frequency, rate or extent of the movement of a cell.

25

0.06

2

32.36

1.77e-03

regulation of viral life cycle

Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.

26

0.06

2

31.12

1.91e-03

striated muscle cell differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.

26

0.06

2

31.12

1.91e-03

actomyosin structure organization and biogenesis

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin. The myosin may be organized into filaments.

27

0.07

2

29.97

2.06e-03

leukocyte chemotaxis

The movement of a leukocyte in response to an external stimulus.

32

0.08

2

25.28

2.88e-03

myoblast development

The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure.

32

0.08

2

25.28

2.88e-03

myoblast maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state.

32

0.08

2

25.28

2.88e-03

muscle development

The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.

256

0.63

4

6.32

3.98e-03

epidermal growth factor receptor signaling pathway

The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands.

38

0.09

2

21.29

4.05e-03

leukocyte migration

The movement of leukocytes within or between different tissues and organs of the body.

39

0.10

2

20.75

4.26e-03

cell cycle arrest

Any process by which progression through the cell cycle is halted during one of the normal phases (G1, S, G2, M).

135

0.33

3

8.99

4.75e-03

myeloid leukocyte activation

A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.

43

0.11

2

18.82

5.16e-03

mitosis

Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.

284

0.70

4

5.70

5.73e-03

calcium-mediated signaling

A series of molecular signals in which a cell uses calcium ions to convert an extracellular signal into a response.

47

0.12

2

17.21

6.14e-03

M phase of mitotic cell cycle

Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place.

290

0.72

4

5.58

6.16e-03

cytokine and chemokine mediated signaling pathway

Any series of molecular signals generated as a consequence of a cytokine or chemokine binding to a cell surface receptor.

50

0.12

2

16.18

6.92e-03

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.

2359

5.83

13

2.23

7.01e-03

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

2359

5.83

13

2.23

7.01e-03

leukocyte activation

A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.

305

0.75

4

5.31

7.33e-03

viral genome replication

Any process involved directly in viral genome replication, including viral nucleotide metabolism.

52

0.13

2

15.56

7.46e-03

myoblast differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a cell type that gives rise to mature contractile cells called myocytes. Fusion of myoblasts gives rise to the myotubes that eventually develop into skeletal muscle fibers.

55

0.14

2

14.71

8.32e-03

B cell differentiation

The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a B cell.

57

0.14

2

14.19

8.91e-03