L2L Microarray Analysis Tool
Results for N05AL.profile.d50
| Results summary | View all lists in L2L MDB | View all genes in N05AL.profile.d50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| tgfb_hmvec_2hr_up | Up-regulated 2 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 1997 | 4.94 | 23 | 4.66 | 2.86e-09 |
| tgfb_hmvec_4hr_up | Up-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 1997 | 4.94 | 23 | 4.66 | 2.86e-09 |
| stemcell_neural_up | Enriched in mouse neural stem cells, compared to differentiated brain and bone marrow cells | 2805 | 6.93 | 18 | 2.60 | 3.17e-04 |
| heatshock_hela_4hr_dn | Down-regulated at 4 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05). | 1829 | 4.52 | 13 | 2.88 | 8.24e-04 |
| erm_ko_testes_dn | Down-regulated in testes from 4 week old ERM knockout mice, compared to wild-type controls | 24 | 0.06 | 2 | 33.71 | 1.63e-03 |
| brca_er_neg | Genes whose expression is consistently negatively correlated with estrogen receptor status in breast cancer - higher expression is associated with ER-negative tumors | 1519 | 3.75 | 11 | 2.93 | 1.73e-03 |
| heartfailure_atria_dn | Downregulated in the atria of failing hearts (DCM and ICM) compared to healthy controls | 213 | 0.53 | 4 | 7.60 | 2.07e-03 |
| ageing_brain_dn | Age-downregulated in the human frontal cortex | 244 | 0.60 | 4 | 6.63 | 3.36e-03 |
| dox_resist_gastric_dn | Downregulated in gastric cancer cell lines reistant to doxorubicin, compared to parent chemosensitive lines | 43 | 0.11 | 2 | 18.82 | 5.16e-03 |
| genotoxins_all_4hrs_reg | Genes regulated in mouse lymphocytes (TK 3.7.2C) at 4 hours by all six genotoxins tested (cisplatin, methyl methanesulfonate, mitomycin C, taxol, hydroxyurea and etoposide) | 45 | 0.11 | 2 | 17.98 | 5.64e-03 |
| et743_sarcoma_dn | Down-regulated following treatment with Et-743 at any timepoint in at least 8 of 11 sarcoma cell lines | 459 | 1.13 | 5 | 4.41 | 6.09e-03 |