Results summary | View all lists in L2L MDB | View all genes in N04BC.profile.ud50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
et743_sarcoma_resist_dn | Constiutively down-regulated in three sarcoma cell lines resistant to Et-743 compared to six sensitive lines | 8 | 0.04 | 2 | 50.57 | 6.71e-04 |
igfr_ir_up | Up-regulated in common following stimulation of chimeric TrkC/IR or TrkC/IGFR in NIH3T3 cells | 36 | 0.18 | 3 | 16.86 | 7.64e-04 |
as3_hek293_dn | Downregulated in HEK293 cells by treatment with arsenite | 12 | 0.06 | 2 | 33.71 | 1.56e-03 |
mmc_res_xenografts_up | Up-regulation is correlated with resistance of human cancer xenografts to mitomycin C | 14 | 0.07 | 2 | 28.90 | 2.14e-03 |
hypoxia_fibro_young_up | Upregulated by hypoxia in normal fibroblasts from young, but not old, donors (Table 1) | 15 | 0.07 | 2 | 26.97 | 2.46e-03 |
tgfb_hmvec_4hr_dn | Down-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 1321 | 6.53 | 15 | 2.30 | 3.01e-03 |
heatshock_young_up | Upregulated after heat shock in lymphocytes from young individuals, compared to old | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
bay_pbmc_2hr_up | Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 606 | 3.00 | 9 | 3.00 | 3.67e-03 |
5azac-tsa_hepg2_up | Up-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC) and 24 hrs treatment with both 5azaC and 500 nM trichostatin A (TSA). | 1966 | 9.72 | 19 | 1.95 | 5.30e-03 |
ifn_gamma_up | Upregulated 2-fold in HT1080 cells 6 hours following treatment with interferon gamma | 80 | 0.40 | 3 | 7.59 | 7.48e-03 |
werner_fibro_up | Upregulated in fibroblasts from individuals with Werner syndrome, compared to normal, young individuals | 81 | 0.40 | 3 | 7.49 | 7.74e-03 |
tgfb_hmvec_2hr_dn | Down-regulated 2 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 353 | 1.75 | 6 | 3.44 | 8.83e-03 |
oldwerner_fibro_up | Commonly upregulated in fibroblasts from Werner Syndrome and old individuals, compared to young | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |