L2L L2L Microarray Analysis Tool

Results for N04BC.profile.ud50

Results summary View all lists in L2L MDB View all genes in N04BC.profile.ud50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
et743_sarcoma_resist_dn Constiutively down-regulated in three sarcoma cell lines resistant to Et-743 compared to six sensitive lines 8 0.04 2 50.57 6.71e-04
igfr_ir_up Up-regulated in common following stimulation of chimeric TrkC/IR or TrkC/IGFR in NIH3T3 cells 36 0.18 3 16.86 7.64e-04
as3_hek293_dn Downregulated in HEK293 cells by treatment with arsenite 12 0.06 2 33.71 1.56e-03
mmc_res_xenografts_up Up-regulation is correlated with resistance of human cancer xenografts to mitomycin C 14 0.07 2 28.90 2.14e-03
hypoxia_fibro_young_up Upregulated by hypoxia in normal fibroblasts from young, but not old, donors (Table 1) 15 0.07 2 26.97 2.46e-03
tgfb_hmvec_4hr_dn Down-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. 1321 6.53 15 2.30 3.01e-03
heatshock_young_up Upregulated after heat shock in lymphocytes from young individuals, compared to old 18 0.09 2 22.47 3.55e-03
bay_pbmc_2hr_up Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 606 3.00 9 3.00 3.67e-03
5azac-tsa_hepg2_up Up-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC) and 24 hrs treatment with both 5azaC and 500 nM trichostatin A (TSA). 1966 9.72 19 1.95 5.30e-03
ifn_gamma_up Upregulated 2-fold in HT1080 cells 6 hours following treatment with interferon gamma 80 0.40 3 7.59 7.48e-03
werner_fibro_up Upregulated in fibroblasts from individuals with Werner syndrome, compared to normal, young individuals 81 0.40 3 7.49 7.74e-03
tgfb_hmvec_2hr_dn Down-regulated 2 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. 353 1.75 6 3.44 8.83e-03
oldwerner_fibro_up Commonly upregulated in fibroblasts from Werner Syndrome and old individuals, compared to young 30 0.15 2 13.48 9.70e-03

Raw data (tab-delimited .txt)