L2L Microarray Analysis Tool

Results summary	View all lists in GO:BiolProc	View all genes in L04AX.profile.ud50

List Name	Description	Total probes	Expected matches	Actual matches	Fold Enrichment	Binomial p-value
positive regulation of transcription	Any process that activates or increases the frequency, rate or extent of transcription.	439	2.17	10	4.61	8.49e-05
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.	450	2.22	10	4.49	1.04e-04
positive regulation of cellular metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.	539	2.66	10	3.75	4.34e-04
histone acetylation	The modification of histones by addition of acetyl groups.	31	0.15	3	19.57	4.90e-04
positive regulation of metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.	567	2.80	10	3.57	6.39e-04
polyamine biosynthetic process	The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.	9	0.04	2	44.95	8.60e-04
protein amino acid acetylation	The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	40	0.20	3	15.17	1.04e-03
G2/M transition DNA damage checkpoint	A cell cycle checkpoint that blocks cell cycle progression from G2 to M phase in response to DNA damage.	11	0.05	2	36.78	1.31e-03
G2/M transition checkpoint	Any cell cycle checkpoint that blocks entry into M phase.	11	0.05	2	36.78	1.31e-03
snRNA metabolic process	The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.	12	0.06	2	33.71	1.56e-03
snRNA processing	Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule.	12	0.06	2	33.71	1.56e-03
protein amino acid acylation	The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid.	52	0.26	3	11.67	2.23e-03
DNA metabolic process	The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.	922	4.56	12	2.63	2.59e-03
positive regulation of transcription, DNA-dependent	Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription.	368	1.82	7	3.85	2.64e-03
mitosis	Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.	284	1.40	6	4.27	3.15e-03
polyamine metabolic process	The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.	17	0.08	2	23.80	3.16e-03
M phase of mitotic cell cycle	Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	290	1.43	6	4.18	3.48e-03
microtubule organizing center organization and biogenesis	A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.	18	0.09	2	22.47	3.55e-03
centrosome organization and biogenesis	A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.	18	0.09	2	22.47	3.55e-03
histone modification	The covalent alteration of one or more amino acid residues within a histone protein.	68	0.34	3	8.92	4.77e-03
covalent chromatin modification	The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.	69	0.34	3	8.79	4.96e-03
regulation of osteoclast differentiation	Any process that modulates the frequency, rate or extent of osteoclast differentiation.	23	0.11	2	17.59	5.77e-03
response to unfolded protein	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	83	0.41	3	7.31	8.27e-03
response to protein stimulus	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus.	83	0.41	3	7.31	8.27e-03
osteoclast differentiation	The process whereby a relatively unspecialized monocyte acquires the specialized features of a osteoclast cell.	28	0.14	2	14.45	8.48e-03
positive regulation of cellular process	Any process that activates or increases the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.	1371	6.78	14	2.07	9.77e-03
RNA-dependent DNA replication	The process whereby new strands of DNA are synthesized, using RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands.	2	0.01	1	101.14	9.86e-03

Any process that activates or increases the frequency, rate or extent of transcription.

439

2.17

4.61

8.49e-05

positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

450

2.22

10

4.49

1.04e-04

positive regulation of cellular metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

539

2.66

10

3.75

4.34e-04

histone acetylation

The modification of histones by addition of acetyl groups.

31

0.15

3

19.57

4.90e-04

positive regulation of metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

567

2.80

10

3.57

6.39e-04

polyamine biosynthetic process

The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.

9

0.04

2

44.95

8.60e-04

protein amino acid acetylation

The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.

40

0.20

3

15.17

1.04e-03

G2/M transition DNA damage checkpoint

A cell cycle checkpoint that blocks cell cycle progression from G2 to M phase in response to DNA damage.

11

0.05

2

36.78

1.31e-03

G2/M transition checkpoint

Any cell cycle checkpoint that blocks entry into M phase.

11

0.05

2

36.78

1.31e-03

snRNA metabolic process

The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.

12

0.06

2

33.71

1.56e-03

snRNA processing

Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule.

12

0.06

2

33.71

1.56e-03

protein amino acid acylation

The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid.

52

0.26

3

11.67

2.23e-03

DNA metabolic process

The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

922

4.56

12

2.63

2.59e-03

positive regulation of transcription, DNA-dependent

Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription.

368

1.82

7

3.85

2.64e-03

mitosis

Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.

284

1.40

6

4.27

3.15e-03

polyamine metabolic process

The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.

17

0.08

2

23.80

3.16e-03

M phase of mitotic cell cycle

Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place.

290

1.43

6

4.18

3.48e-03

microtubule organizing center organization and biogenesis

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.

18

0.09

2

22.47

3.55e-03

centrosome organization and biogenesis

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.

18

0.09

2

22.47

3.55e-03

histone modification

The covalent alteration of one or more amino acid residues within a histone protein.

68

0.34

3

8.92

4.77e-03

covalent chromatin modification

The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.

69

0.34

3

8.79

4.96e-03

regulation of osteoclast differentiation

Any process that modulates the frequency, rate or extent of osteoclast differentiation.

23

0.11

2

17.59

5.77e-03

response to unfolded protein

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.

83

0.41

3

7.31

8.27e-03

response to protein stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus.

83

0.41

3

7.31

8.27e-03

osteoclast differentiation

The process whereby a relatively unspecialized monocyte acquires the specialized features of a osteoclast cell.

28

0.14

2

14.45

8.48e-03

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

1371

6.78

14

2.07

9.77e-03

RNA-dependent DNA replication

The process whereby new strands of DNA are synthesized, using RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands.

2

0.01

1

101.14

9.86e-03

Results for L04AX.profile.ud50