L2L L2L Microarray Analysis Tool

Results for L01XX.profile.ud50

Results summary View all lists in L2L MDB View all genes in L01XX.profile.ud50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
bleo_human_lymph_high_4hrs_up Up-regulated at 4 hours following treatment of human lymphocytes (TK6) with a high dose of bleomycin 32 0.16 4 25.28 1.92e-05
bay_pbmc_2hr_up Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 606 3.00 11 3.67 2.75e-04
dsrna_up Upregulated by dsRNA (polyI:C) in IFN-null GRE cells 68 0.34 4 11.90 3.78e-04
tpa_sens_early_dn Downregulated by TPA at two consecutive timepoints between 15min-3hrs in sensitive HL-60 cells 564 2.79 10 3.59 6.13e-04
heat_glioblastoma_up Up-regulated following 1 hr 43degC heat shock in human glioblastoma cells (U87MG). 78 0.39 4 10.37 6.37e-04
uvc_ttd_all_dn Down-regulated at any timepoint following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC 780 3.86 12 3.11 6.45e-04
bay_pbmc_30min_up up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 82 0.41 4 9.87 7.69e-04
cmv_hcmv_timecourse_14hrs_up Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 14 hours 84 0.42 4 9.63 8.41e-04
caries_pulp_up Up-regulated in pulpal tissue from extracted carious teeth (cavities), compared to tissue from extracted healthy teeth 410 2.03 8 3.95 1.15e-03
hdaci_colon_cluster1 Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 1) 12 0.06 2 33.71 1.56e-03
uvc_ttd_4hr_dn Down-regulated at 4 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC 641 3.17 10 3.16 1.59e-03
et743pt650_colonca_up Upregulated by both Et-743 and Pt-650 in HCT116 cells (Fig. 6D) 13 0.06 2 31.12 1.84e-03
p53_brca1_up Upregulated by expression of p53 in p53-null, brca1-null MEFs; most genes are further upregulated by simultaneous expression of BRCA1 49 0.24 3 12.38 1.88e-03
et743_blockstsa Normally induced by the HDACi TSA, but induction is blocked by Et-743 15 0.07 2 26.97 2.46e-03
et743_sarcoma_24hrs_up Up-regulated at 24 hours following treatment with Et-743 in at least 8 of 11 sarcoma cell lines 16 0.08 2 25.28 2.80e-03
brca_prognosis_pos Genes whose expression is consistently positively correlated with breast cancer outcomes - higher expression is associated with good prognosis 57 0.28 3 10.65 2.90e-03
uvc_low_a2_up Up-regulated at 6-12 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster a2) 17 0.08 2 23.80 3.16e-03
alk1_hmvec_2hr_up Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). 593 2.93 9 3.07 3.19e-03
alk1_hmvec_4hr_up Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). 593 2.93 9 3.07 3.19e-03
uvc_ttd_8hr_dn Down-regulated at 8 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC 382 1.89 7 3.71 3.24e-03
atria_up Upregulated in the atria of healthy hearts, compared to venticles 384 1.90 7 3.69 3.33e-03
il2_pbmc_2hr_up Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 66 0.33 3 9.19 4.38e-03
il2_pbmc_30min_up Up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 66 0.33 3 9.19 4.38e-03
hdaci_colon_tsa12hrs_up Upregulated by TSA at 12 hrs in SW260 colon carcinoma cells 21 0.10 2 19.26 4.82e-03
uvc_low_c1_dn Down-regulated at 6 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster c1) 21 0.10 2 19.26 4.82e-03
hdaci_colon_cur12hrs_up Upregulated by curcumin at 12 hrs in SW260 colon carcinoma cells 22 0.11 2 18.39 5.29e-03
cmv_hcmv_timecourse_4hrs_up Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 4 hours 26 0.13 2 15.56 7.34e-03
cmv_hcmv_timecourse_8hrs_dn Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 8 hours 27 0.13 2 14.98 7.90e-03
il2_pbmc_2hr_dn Down-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 27 0.13 2 14.98 7.90e-03
il2_pbmc_30min_dn Down-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 27 0.13 2 14.98 7.90e-03

Raw data (tab-delimited .txt)