Results summary | View all lists in L2L MDB | View all genes in L01XX.profile.ud50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
bleo_human_lymph_high_4hrs_up | Up-regulated at 4 hours following treatment of human lymphocytes (TK6) with a high dose of bleomycin | 32 | 0.16 | 4 | 25.28 | 1.92e-05 |
bay_pbmc_2hr_up | Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 606 | 3.00 | 11 | 3.67 | 2.75e-04 |
dsrna_up | Upregulated by dsRNA (polyI:C) in IFN-null GRE cells | 68 | 0.34 | 4 | 11.90 | 3.78e-04 |
tpa_sens_early_dn | Downregulated by TPA at two consecutive timepoints between 15min-3hrs in sensitive HL-60 cells | 564 | 2.79 | 10 | 3.59 | 6.13e-04 |
heat_glioblastoma_up | Up-regulated following 1 hr 43degC heat shock in human glioblastoma cells (U87MG). | 78 | 0.39 | 4 | 10.37 | 6.37e-04 |
uvc_ttd_all_dn | Down-regulated at any timepoint following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 780 | 3.86 | 12 | 3.11 | 6.45e-04 |
bay_pbmc_30min_up | up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 82 | 0.41 | 4 | 9.87 | 7.69e-04 |
cmv_hcmv_timecourse_14hrs_up | Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 14 hours | 84 | 0.42 | 4 | 9.63 | 8.41e-04 |
caries_pulp_up | Up-regulated in pulpal tissue from extracted carious teeth (cavities), compared to tissue from extracted healthy teeth | 410 | 2.03 | 8 | 3.95 | 1.15e-03 |
hdaci_colon_cluster1 | Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 1) | 12 | 0.06 | 2 | 33.71 | 1.56e-03 |
uvc_ttd_4hr_dn | Down-regulated at 4 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 641 | 3.17 | 10 | 3.16 | 1.59e-03 |
et743pt650_colonca_up | Upregulated by both Et-743 and Pt-650 in HCT116 cells (Fig. 6D) | 13 | 0.06 | 2 | 31.12 | 1.84e-03 |
p53_brca1_up | Upregulated by expression of p53 in p53-null, brca1-null MEFs; most genes are further upregulated by simultaneous expression of BRCA1 | 49 | 0.24 | 3 | 12.38 | 1.88e-03 |
et743_blockstsa | Normally induced by the HDACi TSA, but induction is blocked by Et-743 | 15 | 0.07 | 2 | 26.97 | 2.46e-03 |
et743_sarcoma_24hrs_up | Up-regulated at 24 hours following treatment with Et-743 in at least 8 of 11 sarcoma cell lines | 16 | 0.08 | 2 | 25.28 | 2.80e-03 |
brca_prognosis_pos | Genes whose expression is consistently positively correlated with breast cancer outcomes - higher expression is associated with good prognosis | 57 | 0.28 | 3 | 10.65 | 2.90e-03 |
uvc_low_a2_up | Up-regulated at 6-12 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster a2) | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
alk1_hmvec_2hr_up | Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). | 593 | 2.93 | 9 | 3.07 | 3.19e-03 |
alk1_hmvec_4hr_up | Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). | 593 | 2.93 | 9 | 3.07 | 3.19e-03 |
uvc_ttd_8hr_dn | Down-regulated at 8 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 382 | 1.89 | 7 | 3.71 | 3.24e-03 |
atria_up | Upregulated in the atria of healthy hearts, compared to venticles | 384 | 1.90 | 7 | 3.69 | 3.33e-03 |
il2_pbmc_2hr_up | Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 66 | 0.33 | 3 | 9.19 | 4.38e-03 |
il2_pbmc_30min_up | Up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 66 | 0.33 | 3 | 9.19 | 4.38e-03 |
hdaci_colon_tsa12hrs_up | Upregulated by TSA at 12 hrs in SW260 colon carcinoma cells | 21 | 0.10 | 2 | 19.26 | 4.82e-03 |
uvc_low_c1_dn | Down-regulated at 6 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster c1) | 21 | 0.10 | 2 | 19.26 | 4.82e-03 |
hdaci_colon_cur12hrs_up | Upregulated by curcumin at 12 hrs in SW260 colon carcinoma cells | 22 | 0.11 | 2 | 18.39 | 5.29e-03 |
cmv_hcmv_timecourse_4hrs_up | Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 4 hours | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |
cmv_hcmv_timecourse_8hrs_dn | Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 8 hours | 27 | 0.13 | 2 | 14.98 | 7.90e-03 |
il2_pbmc_2hr_dn | Down-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 27 | 0.13 | 2 | 14.98 | 7.90e-03 |
il2_pbmc_30min_dn | Down-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 27 | 0.13 | 2 | 14.98 | 7.90e-03 |