L2L L2L Microarray Analysis Tool

Results for J05AB.profile.ud50

Results summary View all lists in L2L MDB View all genes in J05AB.profile.ud50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
avoidance_dn Down-regulated in hippocampi from the Syracuse high-avoidance (SHA) rat line, versus Syracuse low-avoidance (SLA) rat line. 40 0.20 4 20.23 4.74e-05
pdgf_es_dn Down-regulated by PDGF in mouse embryonic stem cells, via microarray-coupled gene-trap mutagenesis 6 0.03 2 67.42 3.62e-04
heatshock_hela_4hr_up Up-regulated at 4 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05). 675 3.34 11 3.30 6.71e-04
il2_pbmc_48hr_up Up-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 511 2.53 9 3.56 1.18e-03
mms_human_lymph_high_4hrs_dn Down-regulated at 4 hours following treatment of human lymphocytes (TK6) with a high dose of methyl methanesulfonate (MMS) 11 0.05 2 36.78 1.31e-03
il2_pbmc_6hr_up Up-regulated at 6hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 530 2.62 9 3.43 1.51e-03
et743_blockstsa Normally induced by the HDACi TSA, but induction is blocked by Et-743 15 0.07 2 26.97 2.46e-03
cisplatin_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with cisplatin 23 0.11 2 17.59 5.77e-03
middleage_dn Downregulated in fibroblasts from middle-age individuals, compared to young 23 0.11 2 17.59 5.77e-03
p21_p53_early_dn Down-regulated at early timepoints (4-8 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells, p53-dependent 23 0.11 2 17.59 5.77e-03
dox_resist_gastric_up Upregulated in gastric cancer cell lines reistant to doxorubicin, compared to parent chemosensitive lines 74 0.37 3 8.20 6.03e-03
cancerdrugs_probcell_up Up-regulated by at least two of four cancer drugs (cisplatin, camptothecin, methotrextate and/or paclitaxel) in pro-B cells (FL5.12) 24 0.12 2 16.86 6.28e-03
methotrexate_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with methotrexate 24 0.12 2 16.86 6.28e-03
bay_pbmc_4hr_up Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 544 2.69 8 2.97 6.33e-03
oldage_dn Downregulated in fibroblasts from old individuals, compared to young 76 0.38 3 7.98 6.49e-03
insulin_adip_insens_dn Down-regulated by insulin in murine adipocytes, and continue to respond following induction of insulin-resistance with TNFalpha treatment 25 0.12 2 16.18 6.80e-03
senescence_hela_dn Down-regulated in HeLa/HPV16E6 cells 6 days following induction of senescence by repression of HPV E7 via HPV E2 and subsequent reactivation of Rb. 341 1.69 6 3.56 7.53e-03
cmv_ie86_up Upregulated by expression of cytomegalovirus IE86 protein in primary human fibroblasts 82 0.41 3 7.40 8.00e-03
camptothecin_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with camptothecin 28 0.14 2 14.45 8.48e-03
uv-cmv_unique_hcmv_6hrs_dn Down-regulated in fibroblasts at 6 hours following infection with UV-inactivated CMV, but not untreated CMV 164 0.81 4 4.93 9.29e-03
cmv_hcmv_timecourse_10hrs_dn Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 10 hours 30 0.15 2 13.48 9.70e-03

Raw data (tab-delimited .txt)