L2L L2L Microarray Analysis Tool

Results for J01DB.profile.d50

Results summary View all lists in L2L MDB View all genes in J01DB.profile.d50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
brca1_mes_up Genes with reduced expression in mouse embryonic stem cells with a targeted deletion of BRCA1, whose expression was rescued by ectopic expression of a BRCA1 transgene 86 0.21 3 14.11 1.33e-03
tnfalpha_adip_dn Downregulated in mature, differentiated adipocytes following treatment with TNFalpha 101 0.25 3 12.02 2.10e-03
hdaci_colon_cluster5 Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 5) 32 0.08 2 25.28 2.88e-03
adip_diff_up Upregulated in mature adipocytes following diffferentiation from 3T3-L1 fibroblasts 123 0.30 3 9.87 3.66e-03
stemcell_embryonic_up Enriched in mouse embryonic stem cells, compared to differentiated brain and bone marrow cells 1989 4.92 12 2.44 4.74e-03
tgz_adip_up Upregulated in mature, differentiated adipocytes following treatment with troglitazone 43 0.11 2 18.82 5.16e-03
stemcell_hematopoietic_up Enriched in mouse hematopoietic stem cells, compared to differentiated brain and bone marrow cells 2092 5.17 12 2.32 6.94e-03
brca1_overexp_prostate_up Up-regulated with stable, ectopic overexpression of BRCA1 in DU-145 human prostate cancer cell lines, compared to neo-only controls 308 0.76 4 5.25 7.58e-03
alzheimers_incipient_dn Downregulated in correlation with incipient Alzheimer's Disease, in the CA1 region of the hippocampus 312 0.77 4 5.19 7.92e-03
et743_sarcoma_24hrs_dn Down-regulated at 24 hours following treatment with Et-743 in at least 8 of 11 sarcoma cell lines 163 0.40 3 7.45 7.98e-03
hdaci_colon_but12hrs_up Upregulated by butyrate at 12 hrs in SW260 colon carcinoma cells 54 0.13 2 14.98 8.03e-03
pod1_ko_dn Down-regulated in glomeruli isolated from Pod1 knockout mice, versus wild-type controls 1135 2.81 8 2.85 8.14e-03
hdaci_colon_but16hrs_dn Downregulated by butyrate at 16 hrs in SW260 colon carcinoma cells 167 0.41 3 7.27 8.52e-03
brca1_overexp_up Upregulated by induction of exogenous BRCA1 in EcR-293 cells 328 0.81 4 4.93 9.39e-03

Raw data (tab-delimited .txt)