Results summary | View all lists in L2L MDB | View all genes in J01DB.profile.d50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
brca1_mes_up | Genes with reduced expression in mouse embryonic stem cells with a targeted deletion of BRCA1, whose expression was rescued by ectopic expression of a BRCA1 transgene | 86 | 0.21 | 3 | 14.11 | 1.33e-03 |
tnfalpha_adip_dn | Downregulated in mature, differentiated adipocytes following treatment with TNFalpha | 101 | 0.25 | 3 | 12.02 | 2.10e-03 |
hdaci_colon_cluster5 | Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 5) | 32 | 0.08 | 2 | 25.28 | 2.88e-03 |
adip_diff_up | Upregulated in mature adipocytes following diffferentiation from 3T3-L1 fibroblasts | 123 | 0.30 | 3 | 9.87 | 3.66e-03 |
stemcell_embryonic_up | Enriched in mouse embryonic stem cells, compared to differentiated brain and bone marrow cells | 1989 | 4.92 | 12 | 2.44 | 4.74e-03 |
tgz_adip_up | Upregulated in mature, differentiated adipocytes following treatment with troglitazone | 43 | 0.11 | 2 | 18.82 | 5.16e-03 |
stemcell_hematopoietic_up | Enriched in mouse hematopoietic stem cells, compared to differentiated brain and bone marrow cells | 2092 | 5.17 | 12 | 2.32 | 6.94e-03 |
brca1_overexp_prostate_up | Up-regulated with stable, ectopic overexpression of BRCA1 in DU-145 human prostate cancer cell lines, compared to neo-only controls | 308 | 0.76 | 4 | 5.25 | 7.58e-03 |
alzheimers_incipient_dn | Downregulated in correlation with incipient Alzheimer's Disease, in the CA1 region of the hippocampus | 312 | 0.77 | 4 | 5.19 | 7.92e-03 |
et743_sarcoma_24hrs_dn | Down-regulated at 24 hours following treatment with Et-743 in at least 8 of 11 sarcoma cell lines | 163 | 0.40 | 3 | 7.45 | 7.98e-03 |
hdaci_colon_but12hrs_up | Upregulated by butyrate at 12 hrs in SW260 colon carcinoma cells | 54 | 0.13 | 2 | 14.98 | 8.03e-03 |
pod1_ko_dn | Down-regulated in glomeruli isolated from Pod1 knockout mice, versus wild-type controls | 1135 | 2.81 | 8 | 2.85 | 8.14e-03 |
hdaci_colon_but16hrs_dn | Downregulated by butyrate at 16 hrs in SW260 colon carcinoma cells | 167 | 0.41 | 3 | 7.27 | 8.52e-03 |
brca1_overexp_up | Upregulated by induction of exogenous BRCA1 in EcR-293 cells | 328 | 0.81 | 4 | 4.93 | 9.39e-03 |