L2L L2L Microarray Analysis Tool

Results for G03DC.profile.u50

Results summary View all lists in L2L MDB View all genes in G03DC.profile.u50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
fsh_human_granulosa_up Up-regulated by FSH in primary human granulosa cells (rFSH-17) 31 0.08 3 39.15 6.45e-05
hdaci_three_up Upregulated in several cell lines by all of TSA, SAHA, and MS-275 8 0.02 2 101.14 1.69e-04
uvc_low_all_dn Down-regulated at any timepoint following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (clusters c1-c5) 115 0.28 4 14.07 2.07e-04
alk5_hmvec_2hr_up Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). 347 0.86 6 6.99 2.58e-04
alk5_hmvec_4hr_up Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). 347 0.86 6 6.99 2.58e-04
adipocyte_brca_up Upregulated in breast cancer cells (MCF-7) treated with adipocyte-conditioned growth media 14 0.03 2 57.79 5.45e-04
et743_blockstsa Normally induced by the HDACi TSA, but induction is blocked by Et-743 15 0.04 2 53.94 6.28e-04
stress_genotoxic_specific_up Genes up-regulated 4 hours following genotoxic stress that discriminate genotoxic from non-genotoxic stress 67 0.17 3 18.11 6.43e-04
bay_pbmc_2hr_up Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 606 1.50 7 4.67 9.00e-04
tsa_panc50_up 50 "most interesting" genes upregulated by TSA treatment in at least one of four pancreatic cancer cell lines, but not in normal (HPDE) cells 77 0.19 3 15.76 9.64e-04
as3_hek293_up Upregulated in HEK293 cells by treatment with arsenite 19 0.05 2 42.58 1.02e-03
hypoxia_reg_up Upregulated by hypoxia in renal cells, and downregulated with reoxygenation 80 0.20 3 15.17 1.08e-03
lvad_heartfailure_up Upregulated in the left ventricle myocardium of patients with heart failure following implantation of a left ventricular assist device 180 0.44 4 8.99 1.12e-03
erm_ko_sertoli_dn Down-regulated in Sertoli cells from both 4 and 10 week old ERM knockout mice, compared to 4 week wild-type controls 29 0.07 2 27.90 2.37e-03
adipogenesis_hmsc_class1_up Up-regulated 1 day following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class I) 31 0.08 2 26.10 2.71e-03
bleo_human_lymph_high_4hrs_up Up-regulated at 4 hours following treatment of human lymphocytes (TK6) with a high dose of bleomycin 32 0.08 2 25.28 2.88e-03
uvc_low_c2_dn Down-regulated at 6-12 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster c2) 34 0.08 2 23.80 3.25e-03
cmvuv-cmv_common_hcmv_6hrs_up Up-regulated in fibroblasts at 6 hours following infection with either human cytomegalovirus (CMV) or UV-inactivated CMV 37 0.09 2 21.87 3.84e-03
xpb_ttd-cs_dn Down-regulated in XPB/TTD fibroblasts (expressing XPB-A355C), compared to XPB/CS fibroblasts (expressing XPB-T296C) 41 0.10 2 19.73 4.70e-03
il1_cornea_up Upregulated in corneal fibroblasts after interleukin-1 treatment (Tables 1 and 2) 136 0.34 3 8.92 4.85e-03
idx_tsa_up_cluster1 Strongly up-regulated at 2 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 1) 44 0.11 2 18.39 5.40e-03
cmv_hcmv_timecourse_12hrs_up Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 12 hours 45 0.11 2 17.98 5.64e-03
oxstress_breastca_up Upregulated by H2O2, Menadione and t-BH in breast cancer cells 45 0.11 2 17.98 5.64e-03
cmv_hcmv_6hrs_up Up-regulated in fibroblasts at 6 hours following infection with human cytomegalovirus (CMV) 46 0.11 2 17.59 5.88e-03
o6bg_resist_medulloblastoma_up Up-regulated in a medulloblastoma cell line resistant to both BCNU and O6-BG, compared to sensitive parent line (D-341 MED) 46 0.11 2 17.59 5.88e-03
ifna_uv-cmv_common_hcmv_6hrs_up Up-regulated in fibroblasts at 6 hours following either infection with UV-inactivated CMV or interferon-alpha 47 0.12 2 17.21 6.14e-03
hypoxia_review Genes known to be induced by hypoxia 160 0.40 3 7.59 7.58e-03
reovirus_hek293_up Up-regulated at any timepoint up to 24 hours following infection of HEK293 cells with reovirus strain T3Abney 491 1.21 5 4.12 8.02e-03
cmv_uv-cmv_common_hcmv_6hrs_dn Down-regulated in fibroblasts at 6 hours following infection with either human cytomegalovirus (CMV) or UV-inactivated CMV 54 0.13 2 14.98 8.03e-03
csb_reliable_up Up-regulated reliably by stable expression of wt CSB in hTERT-immortalized CS1AN CSB-null fibroblasts vs. eGFP-expressing controls (7 of 9 pairwise comparisons). 513 1.27 5 3.94 9.56e-03

Raw data (tab-delimited .txt)