L2L L2L Microarray Analysis Tool

Results for G03DB.profile.ud50

Results summary View all lists in L2L MDB View all genes in G03DB.profile.ud50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
et743_blockstsa Normally induced by the HDACi TSA, but induction is blocked by Et-743 15 0.07 4 53.94 7.81e-07
lvad_heartfailure_up Upregulated in the left ventricle myocardium of patients with heart failure following implantation of a left ventricular assist device 180 0.89 8 8.99 3.92e-06
fsh_human_granulosa_up Up-regulated by FSH in primary human granulosa cells (rFSH-17) 31 0.15 4 26.10 1.69e-05
o6bg_resist_medulloblastoma_up Up-regulated in a medulloblastoma cell line resistant to both BCNU and O6-BG, compared to sensitive parent line (D-341 MED) 46 0.23 4 17.59 8.26e-05
pdgf_es_dn Down-regulated by PDGF in mouse embryonic stem cells, via microarray-coupled gene-trap mutagenesis 6 0.03 2 67.42 3.62e-04
uvc_high_d8_dn Progressively down-regulated through 18 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d8) 70 0.35 4 11.56 4.22e-04
heatshock_hela_4hr_up Up-regulated at 4 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05). 675 3.34 11 3.30 6.71e-04
hdaci_three_up Upregulated in several cell lines by all of TSA, SAHA, and MS-275 8 0.04 2 50.57 6.71e-04
caries_pulp_up Up-regulated in pulpal tissue from extracted carious teeth (cavities), compared to tissue from extracted healthy teeth 410 2.03 8 3.95 1.15e-03
uvc_ttd-xpcs_common_up Up-regulated at any timepoint following treatment of both XPB/CS and XPB/TTD fibroblasts with 3 J/m^2 UVC 44 0.22 3 13.79 1.38e-03
uvc_ttd_8hr_up Up-regulated at 8 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC 47 0.23 3 12.91 1.67e-03
stress_arsenic_specific_up Genes up-regulated 4 hours following arsenic treatment that discriminate arsenic from other stress agents 266 1.32 6 4.56 2.28e-03
fsh_rat_granulosa_up Up-regulated by FSH in immortalized rat granulosa cells (rFSH-17) 15 0.07 2 26.97 2.46e-03
sarcomas_gistromal_up Top 20 positive significant genes associated with GI stromal tumors, versus other soft-tissue tumors. 15 0.07 2 26.97 2.46e-03
bay_pbmc_6hr_up Up-regulated at 6 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 475 2.35 8 3.41 2.85e-03
oldonly_fibro_dn Downregulated in fibroblasts from old (but not Werner) individuals, compared to young 61 0.30 3 9.95 3.51e-03
bay_pbmc_2hr_up Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 606 3.00 9 3.00 3.67e-03
as3_hek293_up Upregulated in HEK293 cells by treatment with arsenite 19 0.09 2 21.29 3.95e-03
cisplatin_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with cisplatin 23 0.11 2 17.59 5.77e-03
cancerdrugs_probcell_up Up-regulated by at least two of four cancer drugs (cisplatin, camptothecin, methotrextate and/or paclitaxel) in pro-B cells (FL5.12) 24 0.12 2 16.86 6.28e-03
methotrexate_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with methotrexate 24 0.12 2 16.86 6.28e-03
bay_pbmc_4hr_up Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 544 2.69 8 2.97 6.33e-03
insulin_adip_insens_dn Down-regulated by insulin in murine adipocytes, and continue to respond following induction of insulin-resistance with TNFalpha treatment 25 0.12 2 16.18 6.80e-03
ageing_brain_up Age-upregulated in the human frontal cortex 446 2.20 7 3.17 7.38e-03
alk5_hmvec_2hr_up Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). 347 1.72 6 3.50 8.16e-03
alk5_hmvec_4hr_up Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). 347 1.72 6 3.50 8.16e-03
camptothecin_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with camptothecin 28 0.14 2 14.45 8.48e-03
uvb_nhek3_c7 Regulated by UV-B light in normal human epidermal keratinocytes, cluster 7 86 0.43 3 7.06 9.11e-03
cmv_hcmv_timecourse_10hrs_dn Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 10 hours 30 0.15 2 13.48 9.70e-03

Raw data (tab-delimited .txt)