L2L L2L Microarray Analysis Tool

Results for G03DB.profile.d50

Results summary View all lists in L2L MDB View all genes in G03DB.profile.d50
List Name Description Total
pdgf_es_dn Down-regulated by PDGF in mouse embryonic stem cells, via microarray-coupled gene-trap mutagenesis 6 0.01 2 134.85 9.11e-05
et743_blockstsa Normally induced by the HDACi TSA, but induction is blocked by Et-743 15 0.04 2 53.94 6.28e-04
cisplatin_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with cisplatin 23 0.06 2 35.18 1.49e-03
cancerdrugs_probcell_up Up-regulated by at least two of four cancer drugs (cisplatin, camptothecin, methotrextate and/or paclitaxel) in pro-B cells (FL5.12) 24 0.06 2 33.71 1.63e-03
methotrexate_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with methotrexate 24 0.06 2 33.71 1.63e-03
insulin_adip_insens_dn Down-regulated by insulin in murine adipocytes, and continue to respond following induction of insulin-resistance with TNFalpha treatment 25 0.06 2 32.36 1.77e-03
camptothecin_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with camptothecin 28 0.07 2 28.90 2.21e-03
cmv_hcmv_timecourse_10hrs_dn Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 10 hours 30 0.07 2 26.97 2.54e-03
adipogenesis_hmsc_class3_up Up-regulated 3-14 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class III) 109 0.27 3 11.13 2.61e-03
avoidance_dn Down-regulated in hippocampi from the Syracuse high-avoidance (SHA) rat line, versus Syracuse low-avoidance (SLA) rat line. 40 0.10 2 20.23 4.48e-03
uvc_ttd-xpcs_common_up Up-regulated at any timepoint following treatment of both XPB/CS and XPB/TTD fibroblasts with 3 J/m^2 UVC 44 0.11 2 18.39 5.40e-03
o6bg_resist_medulloblastoma_up Up-regulated in a medulloblastoma cell line resistant to both BCNU and O6-BG, compared to sensitive parent line (D-341 MED) 46 0.11 2 17.59 5.88e-03
scchn_hpvneg_dn Down-regulated in HPV-negative squamous cell carcinomas of the head and neck (SCCHN) vs. normal oral epithelium. 47 0.12 2 17.21 6.14e-03
uvc_ttd_8hr_up Up-regulated at 8 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC 47 0.12 2 17.21 6.14e-03
zmpste24_ko_up Fifty genes most strongly up-regulated in liver tissue from mice deficient in the lamin-protease Zmpste24/Face1, versus wild-type controls 57 0.14 2 14.19 8.91e-03
hdaci_colon_cluster10 Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 10, associated with histone hyperAc) 60 0.15 2 13.48 9.83e-03

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