L2L Microarray Analysis Tool
Results for G03CC.profile.ud50
| Results summary | View all lists in L2L MDB | View all genes in G03CC.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| alk5_hmvec_2hr_up | Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). | 347 | 1.72 | 20 | 11.66 | 2.46e-15 |
| alk5_hmvec_4hr_up | Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). | 347 | 1.72 | 20 | 11.66 | 2.46e-15 |
| alk1_hmvec_2hr_up | Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). | 593 | 2.93 | 20 | 6.82 | 4.42e-11 |
| alk1_hmvec_4hr_up | Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). | 593 | 2.93 | 20 | 6.82 | 4.42e-11 |
| tgfb_hmvec_4hr_dn | Down-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 1321 | 6.53 | 26 | 3.98 | 6.39e-09 |
| genotoxins_all_24hrs_reg | Genes most consistently regulated in mouse lymphocytes (TK 3.7.2C) at 24 hours by all six genotoxins tested (cisplatin, methyl methanesulfonate, mitomycin C, taxol, hydroxyurea and etoposide) | 49 | 0.24 | 4 | 16.51 | 1.06e-04 |
| atria_up | Upregulated in the atria of healthy hearts, compared to venticles | 384 | 1.90 | 9 | 4.74 | 1.53e-04 |
| uvb_nhek3_c8 | Regulated by UV-B light in normal human epidermal keratinocytes, cluster 8 | 132 | 0.65 | 5 | 7.66 | 5.43e-04 |
| hypoxia_rcc_novhl_up | Upregulated by hypoxia in VHL-null renal carcinoma cells (Fig. 4h+i) | 88 | 0.44 | 4 | 9.19 | 1.00e-03 |
| cmv-uv_hcmv_6hrs_up | Up-regulated in fibroblasts at 6 hours following infection with UV-inactivated human cytomegalovirus | 226 | 1.12 | 6 | 5.37 | 1.00e-03 |
| cmv_hcmv_timecourse_16hrs_up | Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 16 hours | 93 | 0.46 | 4 | 8.70 | 1.23e-03 |
| et743_resist_dn | Down-regulated in two Et-743-resistant cell lines (chondrosarcoma and ovarian carcinoma) compared to sensitive parental lines | 95 | 0.47 | 4 | 8.52 | 1.33e-03 |
| il2_pbmc_6hr_up | Up-regulated at 6hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 530 | 2.62 | 9 | 3.43 | 1.51e-03 |
| sarcomas_leiomyosarcoma_up | Top 20 positive significant genes associated with calponin negative leiomyosarcoma tumors, versus other soft-tissue tumors. | 12 | 0.06 | 2 | 33.71 | 1.56e-03 |
| vhl_normal_up | Upregulated in VHL-null renal carcinoma vs. normal renal cells (Fig. 2c+e) | 754 | 3.73 | 11 | 2.95 | 1.61e-03 |
| cmv_all_up | Upregulated at any timepoint following infection of primary human foreskin fibroblasts with CMV | 173 | 0.86 | 5 | 5.85 | 1.81e-03 |
| idx_tsa_up_cluster2 | Strongly up-regulated at 8 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 2) | 105 | 0.52 | 4 | 7.71 | 1.92e-03 |
| hdaci_colon_cur48hrs_up | Upregulated by curcumin at 48 hrs in SW260 colon carcinoma cells | 109 | 0.54 | 4 | 7.42 | 2.20e-03 |
| il2_pbmc_2hr_up | Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 66 | 0.33 | 3 | 9.19 | 4.38e-03 |
| il2_pbmc_30min_up | Up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 66 | 0.33 | 3 | 9.19 | 4.38e-03 |
| cmv_24hrs_up | Upregulated at 24hrs following infection of primary human foreskin fibroblasts with CMV | 133 | 0.66 | 4 | 6.08 | 4.49e-03 |
| as3_fibro_c1 | Upregulated strongly by sodium arsenite in fibroblasts (Cluster 1) | 67 | 0.33 | 3 | 9.06 | 4.57e-03 |
| as3_fibro_c2 | Upregulated moderately by sodium arsenite in fibroblasts (Cluster 2) | 67 | 0.33 | 3 | 9.06 | 4.57e-03 |
| oxstress_rpe_h2o2tbh_dn | Downregulated by H2O2 and t-BH in retinal pigment epithelium cells (Tables 5) | 67 | 0.33 | 3 | 9.06 | 4.57e-03 |
| cmv_hcmv_timecourse_all_up | Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints) | 895 | 4.42 | 11 | 2.49 | 5.79e-03 |
| hdaci_colon_cur24hrs_up | Upregulated by curcumin at 24 hrs in SW260 colon carcinoma cells | 73 | 0.36 | 3 | 8.31 | 5.81e-03 |
| vegf_huvec_up | 20 genes with the largest fold-change up-regulation at any time point (30min to 24 hours) after VEGF treatment in human umbilical vein endothelial cells | 24 | 0.12 | 2 | 16.86 | 6.28e-03 |
| hdaci_colon_sul30min_dn | Downregulated by sulindac at 30 min in SW260 colon carcinoma cells | 79 | 0.39 | 3 | 7.68 | 7.22e-03 |
| bay_pbmc_30min_up | up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 82 | 0.41 | 3 | 7.40 | 8.00e-03 |