Results summary | View all lists in L2L MDB | View all genes in G02CB.profile.d50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
stemcell_embryonic_up | Enriched in mouse embryonic stem cells, compared to differentiated brain and bone marrow cells | 1989 | 4.92 | 15 | 3.05 | 1.85e-04 |
5azac_hepg2_dn | Down-regulated in human hepatoma cells (HepG2) following 48 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC). | 1830 | 4.52 | 14 | 3.09 | 2.59e-04 |
5azac-tsa_hepg2_dn | Down-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC) and 24 hrs treatment with both 5azaC and 500 nM trichostatin A (TSA). | 2343 | 5.79 | 16 | 2.76 | 3.43e-04 |
cantharidin_dn | Downregulated in HL-60 promyeloid leukemic cells after treatment with the cytotoxic drug cantharidin | 83 | 0.21 | 3 | 14.62 | 1.20e-03 |
brca1_overexp_dn | Downregulated by induction of exogenous BRCA1 in EcR-293 cells | 220 | 0.54 | 4 | 7.36 | 2.32e-03 |
scchn_hpvpos_up | Up-regulated in HPV-positive squamous cell carcinomas of the head and neck (SCCHN) vs. normal oral epithelium. | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
igfr_ir_up | Up-regulated in common following stimulation of chimeric TrkC/IR or TrkC/IGFR in NIH3T3 cells | 36 | 0.09 | 2 | 22.47 | 3.64e-03 |
stemcell_neural_up | Enriched in mouse neural stem cells, compared to differentiated brain and bone marrow cells | 2805 | 6.93 | 15 | 2.16 | 5.21e-03 |
serum_fibroblast_core_up | Core group of genes consistently up-regulated following exposure to serum in a variety of human fibroblast cell lines (higher expression in activated cells, not cell-cycle dependent) | 292 | 0.72 | 4 | 5.54 | 6.31e-03 |
irs1_ko_adip_up | Up-regulated in brown preadipocytes from Irs1-knockout mice, which display severe defects in adipocyte differentiation, versus wild-type controls | 159 | 0.39 | 3 | 7.63 | 7.45e-03 |
oldonly_fibro_up | Upregulated in fibroblasts from old (but not Werner) individuals, compared to young | 54 | 0.13 | 2 | 14.98 | 8.03e-03 |