Results summary | View all lists in GO:MoleFunc | View all genes in G01AF.profile.ud50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
structure-specific DNA binding | Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. | 142 | 0.70 | 6 | 8.55 | 8.42e-05 |
unfolded protein binding | Interacting selectively with an unfolded protein. | 148 | 0.73 | 6 | 8.20 | 1.06e-04 |
RNA binding | Interacting selectively with an RNA molecule or a portion thereof. | 982 | 4.85 | 15 | 3.09 | 1.58e-04 |
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. | 25 | 0.12 | 3 | 24.27 | 2.56e-04 |
cyclin-dependent protein kinase regulator activity | Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins. | 7 | 0.03 | 2 | 57.79 | 5.05e-04 |
chaperone regulator activity | Modulates the activity of a molecular chaperone. | 7 | 0.03 | 2 | 57.79 | 5.05e-04 |
ribonuclease H activity | Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters. | 8 | 0.04 | 2 | 50.57 | 6.71e-04 |
ATP binding | Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. | 1792 | 8.86 | 20 | 2.26 | 8.49e-04 |
MutLalpha complex binding | Interacting selectively with the mismatch repair complex MutLalpha. | 9 | 0.04 | 2 | 44.95 | 8.60e-04 |
double-stranded DNA binding | Interacting selectively with double-stranded DNA. | 88 | 0.44 | 4 | 9.19 | 1.00e-03 |
nucleotide binding | Interacting selectively with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety. | 2671 | 13.21 | 26 | 1.97 | 1.16e-03 |
mismatch repair complex binding | Interacting selectively with a mismatch repair complex. | 11 | 0.05 | 2 | 36.78 | 1.31e-03 |
exodeoxyribonuclease activity | Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule. | 12 | 0.06 | 2 | 33.71 | 1.56e-03 |
exodeoxyribonuclease activity, producing 5'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. | 12 | 0.06 | 2 | 33.71 | 1.56e-03 |
transferase activity, transferring nitrogenous groups | Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor). | 46 | 0.23 | 3 | 13.19 | 1.56e-03 |
adenyl nucleotide binding | Interacting selectively with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate. | 1902 | 9.40 | 20 | 2.13 | 1.70e-03 |
L-glutamate transporter activity | Enables the directed movement of L-glutamate, the anion of 2-aminopentanedioic acid, into, out of, within or between cells. | 13 | 0.06 | 2 | 31.12 | 1.84e-03 |
acidic amino acid transporter activity | Enables the directed movement of acidic amino acids, amino acids with a pH below 7, into, out of, within or between cells. | 14 | 0.07 | 2 | 28.90 | 2.14e-03 |
damaged DNA binding | Interacting selectively with damaged DNA. | 56 | 0.28 | 3 | 10.84 | 2.75e-03 |
amino acid permease activity | Catalysis of the stereospecific transfer of amino acids, organic acids containing one or more amino substituents, across a biological membrane. | 16 | 0.08 | 2 | 25.28 | 2.80e-03 |
low-density lipoprotein receptor binding | Interacting selectively with a low density lipoprotein receptor. | 16 | 0.08 | 2 | 25.28 | 2.80e-03 |
ADP binding | Interacting selectively with ADP, adenosine 5'-diphosphate. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
exonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. | 61 | 0.30 | 3 | 9.95 | 3.51e-03 |
purine nucleotide binding | Interacting selectively with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate. | 2328 | 11.51 | 22 | 1.91 | 3.72e-03 |
DNA N-glycosylase activity | Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. | 19 | 0.09 | 2 | 21.29 | 3.95e-03 |
tRNA binding | Interacting selectively with transfer RNA. | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
heat shock protein binding | Interacting selectvely with a heat shock protein, any protein synthesized or activated in response to heat shock. | 66 | 0.33 | 3 | 9.19 | 4.38e-03 |
ribonuclease activity | Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. | 67 | 0.33 | 3 | 9.06 | 4.57e-03 |
solute:solute antiporter activity | Catalysis of the reaction: solute A(out) + solute B(in) = solute A(in) + solute B(out). | 21 | 0.10 | 2 | 19.26 | 4.82e-03 |
endodeoxyribonuclease activity | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. | 22 | 0.11 | 2 | 18.39 | 5.29e-03 |
hydrolase activity, hydrolyzing N-glycosyl compounds | 22 | 0.11 | 2 | 18.39 | 5.29e-03 | |
single-stranded DNA binding | Interacting selectively with single-stranded DNA. | 72 | 0.36 | 3 | 8.43 | 5.59e-03 |
neutral amino acid transporter activity | Enables the directed movement of neutral amino acids, amino acids with no net charge, into, out of, within or between cells. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
thyroid hormone receptor binding | Interacting selectively with a thyroid hormone receptor. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
amino acid-polyamine transporter activity | 26 | 0.13 | 2 | 15.56 | 7.34e-03 | |
polyamine transporter activity | Enables the directed movement of polyamines, organic compounds containing two or more amino groups, into, out of, within or between cells. | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |
mismatched DNA binding | Interacting selectively with double-stranded DNA containing one or more mismatches. | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |
protein dimerization activity | The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. | 447 | 2.21 | 7 | 3.17 | 7.47e-03 |
endoribonuclease activity, producing 5'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |