L2L L2L Microarray Analysis Tool

Results for D10AA.profile.ud50

Results summary View all lists in GO:BiolProc View all genes in D10AA.profile.ud50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
regulation of interleukin-6 biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6. 8 0.04 3 75.85 6.64e-06
interleukin-6 production The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. 10 0.05 3 60.68 1.41e-05
interleukin-6 biosynthetic process The chemical reactions and pathways resulting in the formation of interleukin-6. 10 0.05 3 60.68 1.41e-05
cytokine production The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. 153 0.76 6 7.93 1.27e-04
B cell proliferation The rapid expansion of a B cell population by cell division. Follows B cell activation. 27 0.13 3 22.47 3.23e-04
positive regulation of interleukin-6 biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6. 7 0.03 2 57.79 5.05e-04
transcription from RNA polymerase II promoter The synthesis of RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). 997 4.93 14 2.84 5.86e-04
regulation of chemokine biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines. 8 0.04 2 50.57 6.71e-04
chemokine production The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. 9 0.04 2 44.95 8.60e-04
chemokine biosynthetic process The chemical reactions and pathways resulting in the formation of chemokines, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions. 9 0.04 2 44.95 8.60e-04
chemokine metabolic process The chemical reactions and pathways involving chemokines, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions. 9 0.04 2 44.95 8.60e-04
regulation of cytokine biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. 85 0.42 4 9.52 8.79e-04
positive regulation of B cell proliferation Any process that activates or increases the rate or extent of B cell proliferation. 10 0.05 2 40.45 1.07e-03
acute-phase response Process involving non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals. 44 0.22 3 13.79 1.38e-03
cytokine biosynthetic process The chemical reactions and pathways resulting in the formation of cytokines, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. 99 0.49 4 8.17 1.55e-03
thermoregulation A homeostatic process by which an organism modulates its internal body temperature. 12 0.06 2 33.71 1.56e-03
serine family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. 12 0.06 2 33.71 1.56e-03
cytokine metabolic process The chemical reactions and pathways involving cytokines, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. 100 0.49 4 8.09 1.61e-03
regulation of B cell proliferation Any process that modulates the frequency, rate or extent of B cell proliferation. 16 0.08 2 25.28 2.80e-03
regulation of transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. 701 3.47 10 2.89 3.01e-03
positive regulation of cytokine biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. 58 0.29 3 10.46 3.04e-03
negative regulation of transcription from RNA polymerase II promoter Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. 201 0.99 5 5.03 3.45e-03
adrenal gland development The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells. 18 0.09 2 22.47 3.55e-03
interleukin-12 production The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. 18 0.09 2 22.47 3.55e-03
regulation of isotype switching Any process that modulates the frequency, rate or extent of isotype switching. 18 0.09 2 22.47 3.55e-03
regulation of transcription, DNA-dependent Any process that modulates the frequency, rate or extent of DNA-dependent transcription. 2510 12.41 23 1.85 4.41e-03
response to metal ion A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. 21 0.10 2 19.26 4.82e-03
regulation of transforming growth factor beta receptor signaling pathway Any process that modulates the frequency, rate or extent of activity of any TGFbeta receptor signaling pathway. 21 0.10 2 19.26 4.82e-03
regulation of progression through cell cycle Any process that modulates the rate or extent of progression through the cell cycle. 875 4.33 11 2.54 4.92e-03
positive regulation of protein biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. 69 0.34 3 8.79 4.96e-03
regulation of cell cycle A cell cycle process that modulates the rate, extent or mode of the cell cycle. 880 4.35 11 2.53 5.13e-03
response to external stimulus A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. 759 3.75 10 2.66 5.21e-03
positive regulation of cellular biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. 75 0.37 3 8.09 6.26e-03
transcription, DNA-dependent The synthesis of RNA on a template of DNA. 2588 12.79 23 1.80 6.26e-03
determination of left/right symmetry The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry. 24 0.12 2 16.86 6.28e-03
neutrophil chemotaxis The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. 24 0.12 2 16.86 6.28e-03
RNA biosynthetic process The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. 2591 12.81 23 1.80 6.34e-03
positive regulation of B cell activation Any process that activates or increases the frequency, rate or extent of B cell activation. 25 0.12 2 16.18 6.80e-03
negative regulation of transcription Any process that stops, prevents or reduces the frequency, rate or extent of transcription. 439 2.17 7 3.23 6.80e-03
determination of symmetry The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created. 26 0.13 2 15.56 7.34e-03
determination of bilateral symmetry The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry. 26 0.13 2 15.56 7.34e-03
response to wounding A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. 560 2.77 8 2.89 7.47e-03
response to inorganic substance A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. 27 0.13 2 14.98 7.90e-03
somatic recombination of immunoglobulin genes during immune response The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. 30 0.15 2 13.48 9.70e-03
somatic diversification of immunoglobulins during immune response The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response. 30 0.15 2 13.48 9.70e-03
immunoglobulin production during immune response The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. 30 0.15 2 13.48 9.70e-03
isotype switching The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. 30 0.15 2 13.48 9.70e-03

Raw data (tab-delimited .txt)