L2L Microarray Analysis Tool
Results for D07XB.profile.u50
| Results summary | View all lists in GO:BiolProc | View all genes in D07XB.profile.u50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| B cell activation | The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. | 115 | 0.28 | 4 | 14.07 | 2.07e-04 |
| immune system development | The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. | 346 | 0.86 | 6 | 7.02 | 2.55e-04 |
| positive regulation of B cell proliferation | Any process that activates or increases the rate or extent of B cell proliferation. | 10 | 0.02 | 2 | 80.91 | 2.71e-04 |
| insulin receptor signaling pathway | The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. | 51 | 0.13 | 3 | 23.80 | 2.88e-04 |
| B cell differentiation | The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a B cell. | 57 | 0.14 | 3 | 21.29 | 4.00e-04 |
| regulation of B cell proliferation | Any process that modulates the frequency, rate or extent of B cell proliferation. | 16 | 0.04 | 2 | 50.57 | 7.17e-04 |
| regulation of actin filament length | Any process that controls the length of actin filaments in a cell. | 73 | 0.18 | 3 | 16.62 | 8.25e-04 |
| regulation of isotype switching | Any process that modulates the frequency, rate or extent of isotype switching. | 18 | 0.04 | 2 | 44.95 | 9.11e-04 |
| hemopoiesis | The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. | 303 | 0.75 | 5 | 6.68 | 1.03e-03 |
| response to metal ion | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. | 21 | 0.05 | 2 | 38.53 | 1.24e-03 |
| hemopoietic or lymphoid organ development | The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. | 323 | 0.80 | 5 | 6.26 | 1.37e-03 |
| negative regulation of cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation. | 90 | 0.22 | 3 | 13.48 | 1.51e-03 |
| positive regulation of cell proliferation | Any process that activates or increases the rate or extent of cell proliferation. | 338 | 0.84 | 5 | 5.98 | 1.67e-03 |
| positive regulation of B cell activation | Any process that activates or increases the frequency, rate or extent of B cell activation. | 25 | 0.06 | 2 | 32.36 | 1.77e-03 |
| response to inorganic substance | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. | 27 | 0.07 | 2 | 29.97 | 2.06e-03 |
| B cell proliferation | The rapid expansion of a B cell population by cell division. Follows B cell activation. | 27 | 0.07 | 2 | 29.97 | 2.06e-03 |
| negative regulation of myeloid cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of myeloid cell differentiation. | 27 | 0.07 | 2 | 29.97 | 2.06e-03 |
| somatic recombination of immunoglobulin genes during immune response | The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
| somatic diversification of immunoglobulins during immune response | The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
| immunoglobulin production during immune response | The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
| isotype switching | The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
| negative regulation of developmental process | Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). | 110 | 0.27 | 3 | 11.03 | 2.68e-03 |
| somatic diversification of immune receptors via germline recombination within a single locus | The process by which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus. | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
| somatic cell DNA recombination | Recombination occurring within or between DNA molecules in somatic cells. | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
| somatic recombination of immunoglobulin gene segments | The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus. | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
| somatic diversification of immune receptors | The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences. | 34 | 0.08 | 2 | 23.80 | 3.25e-03 |
| circadian rhythm | The biological processes in an organism that recur with a regularity of approximately 24 hours. | 34 | 0.08 | 2 | 23.80 | 3.25e-03 |
| somatic diversification of immunoglobulins | The somatic process by means of which sequence diversity of immunoglobulins is generated. | 34 | 0.08 | 2 | 23.80 | 3.25e-03 |
| regulation of B cell activation | Any process that modulates the frequency, rate or extent of B cell activation. | 38 | 0.09 | 2 | 21.29 | 4.05e-03 |
| lymphocyte differentiation | The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells. | 128 | 0.32 | 3 | 9.48 | 4.10e-03 |
| regulation of cytokine production | Any process that modulates the frequency, rate, or extent of production of a cytokine. | 39 | 0.10 | 2 | 20.75 | 4.26e-03 |
| immunoglobulin production | The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. | 39 | 0.10 | 2 | 20.75 | 4.26e-03 |
| lymphocyte activation | A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. | 269 | 0.66 | 4 | 6.02 | 4.74e-03 |
| positive regulation of mononuclear cell proliferation | Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation. | 43 | 0.11 | 2 | 18.82 | 5.16e-03 |
| positive regulation of lymphocyte proliferation | Any process that activates or increases the rate or extent of lymphocyte proliferation. | 43 | 0.11 | 2 | 18.82 | 5.16e-03 |
| myeloid cell differentiation | The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. | 142 | 0.35 | 3 | 8.55 | 5.46e-03 |
| cytokine production | The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. | 153 | 0.38 | 3 | 7.93 | 6.71e-03 |
| cytokine and chemokine mediated signaling pathway | Any series of molecular signals generated as a consequence of a cytokine or chemokine binding to a cell surface receptor. | 50 | 0.12 | 2 | 16.18 | 6.92e-03 |
| production of molecular mediator of immune response | The synthesis or release of any molecular mediator of the immune response following an immunological stimulus, resulting in an increase in its intracellular or extracellular levels. | 51 | 0.13 | 2 | 15.86 | 7.19e-03 |
| leukocyte activation | A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. | 305 | 0.75 | 4 | 5.31 | 7.33e-03 |
| actin cytoskeleton organization and biogenesis | A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. | 313 | 0.77 | 4 | 5.17 | 8.01e-03 |
| erythrocyte differentiation | The process by which a myeloid precursor cell acquires specializes features of an erythrocyte. | 54 | 0.13 | 2 | 14.98 | 8.03e-03 |
| immune system process | Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. | 1134 | 2.80 | 8 | 2.85 | 8.10e-03 |
| regulation of cell proliferation | Any process that modulates the frequency, rate or extent of cell proliferation. | 704 | 1.74 | 6 | 3.45 | 8.81e-03 |
| cell proliferation | The multiplication or reproduction of cells, resulting in the rapid expansion of a cell population. | 1154 | 2.85 | 8 | 2.80 | 8.93e-03 |
| cell activation | A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. | 330 | 0.82 | 4 | 4.90 | 9.59e-03 |