L2L L2L Microarray Analysis Tool

Probes from D01AC.profile.ud50 that match senescence_hff_dn

Results summary View all lists in L2L MDB View all genes in D01AC.profile.ud50

senescence_hff_dn

Down-regulated in primary human foreskin fibroblasts at replicative senescence (passage 26) compared to active replication (passage 8).

enrichment: 8.79-fold
p-value: 5.34e-09

 image image
Probe ID Name G T D X E P R C S image image Description
212141_AT MCM4 G           R     image image minichromosome maintenance complex component 4
220085_AT HELLS G   D       R     image image helicase, lymphoid-specific
204603_AT EXO1 G     X           image image exonuclease 1
209891_AT SPC25                   image image SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
201890_AT RRM2 G                 image image ribonucleotide reductase M2 polypeptide
202532_S_AT DHFR                   image image dihydrofolate reductase
205047_S_AT ASNS                   image image asparagine synthetase
214727_AT BRCA2       X     R     image image breast cancer 2, early onset
218350_S_AT GMNN G   D             image image geminin, DNA replication inhibitor
221677_S_AT DONSON     D             image image downstream neighbor of SON
212295_S_AT SLC7A1   T               image image solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
212023_S_AT MKI67 G                 image image antigen identified by monoclonal antibody Ki-67
222037_AT MCM4 G           R     image image minichromosome maintenance complex component 4