L2L Microarray Analysis Tool
Results for D01AC.profile.ud50
| Results summary | View all lists in GO:BiolProc | View all genes in D01AC.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| DNA replication | The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. | 277 | 1.37 | 14 | 10.22 | 1.99e-10 |
| DNA-dependent DNA replication | The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. | 140 | 0.69 | 10 | 14.45 | 2.79e-09 |
| DNA metabolic process | The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. | 922 | 4.56 | 18 | 3.95 | 1.41e-06 |
| regulation of DNA metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. | 80 | 0.40 | 5 | 12.64 | 5.22e-05 |
| DNA replication initiation | The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action. | 44 | 0.22 | 4 | 18.39 | 6.92e-05 |
| cell cycle process | A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. | 1144 | 5.66 | 17 | 3.01 | 8.34e-05 |
| regulation of progression through cell cycle | Any process that modulates the rate or extent of progression through the cell cycle. | 875 | 4.33 | 14 | 3.24 | 1.61e-04 |
| regulation of cell cycle | A cell cycle process that modulates the rate, extent or mode of the cell cycle. | 880 | 4.35 | 14 | 3.22 | 1.71e-04 |
| tRNA aminoacylation for protein translation | The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis. | 56 | 0.28 | 4 | 14.45 | 1.79e-04 |
| amino acid activation | The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. | 56 | 0.28 | 4 | 14.45 | 1.79e-04 |
| tRNA aminoacylation | The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. | 56 | 0.28 | 4 | 14.45 | 1.79e-04 |
| amino acid transport | The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of, within or between cells. | 62 | 0.31 | 4 | 13.05 | 2.65e-04 |
| negative regulation of DNA metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. | 28 | 0.14 | 3 | 21.67 | 3.61e-04 |
| amino acid metabolic process | The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents. | 344 | 1.70 | 8 | 4.70 | 3.70e-04 |
| negative regulation of apoptosis | Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis. | 345 | 1.71 | 8 | 4.69 | 3.77e-04 |
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. | 1307 | 6.46 | 17 | 2.63 | 3.87e-04 |
| negative regulation of programmed cell death | Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 347 | 1.72 | 8 | 4.66 | 3.91e-04 |
| response to stress | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). | 1358 | 6.71 | 17 | 2.53 | 5.90e-04 |
| mismatch repair | A system for the correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. | 34 | 0.17 | 3 | 17.85 | 6.45e-04 |
| M phase | Progression through M phase, the part of the cell cycle comprising nuclear division and cytokinesis. | 375 | 1.85 | 8 | 4.32 | 6.49e-04 |
| amine transport | The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of, within or between cells. | 79 | 0.39 | 4 | 10.24 | 6.68e-04 |
| M phase of mitotic cell cycle | Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place. | 290 | 1.43 | 7 | 4.88 | 6.82e-04 |
| cell cycle phase | A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. | 474 | 2.34 | 9 | 3.84 | 7.01e-04 |
| maintenance of fidelity during DNA-dependent DNA replication | The correction of errors made during DNA replication by either intrinsic DNA polymerase proofreading activity or via mismatch repair. | 35 | 0.17 | 3 | 17.34 | 7.03e-04 |
| cell division | The processes resulting in the physical partitioning and separation of a cell into daughter cells. | 297 | 1.47 | 7 | 4.77 | 7.84e-04 |
| regulation of DNA replication | Any process that modulates the frequency, rate or extent of DNA replication. | 38 | 0.19 | 3 | 15.97 | 8.96e-04 |
| DNA recombination | The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. | 158 | 0.78 | 5 | 6.40 | 1.22e-03 |
| response to hypoxia | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. | 43 | 0.21 | 3 | 14.11 | 1.29e-03 |
| mitotic cell cycle | Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, in which a cell is duplicated without changing ploidy; comprises four successive phases called G1, S, G2, and M. | 421 | 2.08 | 8 | 3.84 | 1.36e-03 |
| organic acid transport | The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of, within or between cells. | 97 | 0.48 | 4 | 8.34 | 1.44e-03 |
| carboxylic acid transport | The directed movement of carboxylic acids into, out of, within or between cells. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). | 97 | 0.48 | 4 | 8.34 | 1.44e-03 |
| tRNA metabolic process | The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. | 100 | 0.49 | 4 | 8.09 | 1.61e-03 |
| amino acid and derivative metabolic process | The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids. | 440 | 2.18 | 8 | 3.68 | 1.78e-03 |
| regulation of apoptosis | Any process that modulates the occurrence or rate of cell death by apoptosis. | 785 | 3.88 | 11 | 2.83 | 2.20e-03 |
| regulation of programmed cell death | Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 793 | 3.92 | 11 | 2.81 | 2.37e-03 |
| anti-apoptosis | A process which directly inhibits any of the steps required for cell death by apoptosis. | 278 | 1.37 | 6 | 4.37 | 2.84e-03 |
| response to radiation | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. | 117 | 0.58 | 4 | 6.92 | 2.84e-03 |
| regulation of progression through mitotic cell cycle | Any process that modulates the rate or extent of progress through the mitotic cell cycle. | 57 | 0.28 | 3 | 10.65 | 2.90e-03 |
| mitosis | Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. | 284 | 1.40 | 6 | 4.27 | 3.15e-03 |
| induction of apoptosis by intracellular signals | Any process induced by intracellular signals that directly activates any of the steps required for cell death by apoptosis. | 59 | 0.29 | 3 | 10.28 | 3.20e-03 |
| apoptosis | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. | 1078 | 5.33 | 13 | 2.44 | 3.36e-03 |
| regulation of DNA recombination | Any process that modulates the frequency, rate or extent of DNA recombination, a process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
| programmed cell death | Cell death resulting from activation of endogenous cellular processes. | 1086 | 5.37 | 13 | 2.42 | 3.57e-03 |
| traversing start control point of mitotic cell cycle | Passage through a cell cycle control point late in G1 phase of the mitotic cell cycle just before entry into S phase; in most organisms studied, including budding yeast and animal cells, passage through start normally commits the cell to progressing through the entire cell cycle. | 19 | 0.09 | 2 | 21.29 | 3.95e-03 |
| interphase of mitotic cell cycle | Progression through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs. | 134 | 0.66 | 4 | 6.04 | 4.61e-03 |
| response to DNA damage stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. | 412 | 2.04 | 7 | 3.44 | 4.87e-03 |
| interphase | Progression through interphase, the stage of cell cycle between successive rounds of chromosome segregation. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs. | 138 | 0.68 | 4 | 5.86 | 5.11e-03 |
| cell death | The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. | 1152 | 5.70 | 13 | 2.28 | 5.76e-03 |
| death | A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. | 1152 | 5.70 | 13 | 2.28 | 5.76e-03 |
| amine metabolic process | The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. | 538 | 2.66 | 8 | 3.01 | 5.94e-03 |
| DNA unwinding during replication | The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication. | 24 | 0.12 | 2 | 16.86 | 6.28e-03 |
| DNA geometric change | The process by which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases. | 24 | 0.12 | 2 | 16.86 | 6.28e-03 |
| DNA duplex unwinding | The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands. | 24 | 0.12 | 2 | 16.86 | 6.28e-03 |
| G2/M transition of mitotic cell cycle | Progression from G2 phase to M phase of the mitotic cell cycle. | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |
| carboxylic acid metabolic process | The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). | 679 | 3.36 | 9 | 2.68 | 7.51e-03 |
| organic acid metabolic process | The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. | 681 | 3.37 | 9 | 2.67 | 7.65e-03 |
| response to endogenous stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endogenous stimulus. | 453 | 2.24 | 7 | 3.13 | 8.00e-03 |
| response to unfolded protein | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus. | 83 | 0.41 | 3 | 7.31 | 8.27e-03 |
| response to protein stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus. | 83 | 0.41 | 3 | 7.31 | 8.27e-03 |
| nitrogen compound metabolic process | The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium. | 580 | 2.87 | 8 | 2.79 | 9.10e-03 |
| somatic recombination of immunoglobulin genes during immune response | The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| somatic diversification of immunoglobulins during immune response | The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| immunoglobulin production during immune response | The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| isotype switching | The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |