L2L L2L Microarray Analysis Tool

Results for A07EA.profile.ud50

Results summary View all lists in GO:BiolProc View all genes in A07EA.profile.ud50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
negative regulation of B cell activation Any process that stops, prevents or reduces the frequency, rate or extent of B cell activation. 11 0.05 3 55.16 1.94e-05
regulation of B cell proliferation Any process that modulates the frequency, rate or extent of B cell proliferation. 16 0.08 3 37.93 6.45e-05
B cell proliferation The rapid expansion of a B cell population by cell division. Follows B cell activation. 27 0.13 3 22.47 3.23e-04
negative regulation of transcription Any process that stops, prevents or reduces the frequency, rate or extent of transcription. 439 2.17 9 4.15 4.07e-04
negative regulation of transcription from RNA polymerase II promoter Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. 201 0.99 6 6.04 5.46e-04
negative regulation of lymphocyte activation Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte activation. 34 0.17 3 17.85 6.45e-04
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. 478 2.36 9 3.81 7.43e-04
regulation of Rho GTPase activity Any process that modulates the activity of a GTPase of the Rho family. 9 0.04 2 44.95 8.60e-04
negative regulation of small GTPase mediated signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase mediated signal transduction. 9 0.04 2 44.95 8.60e-04
regulation of B cell activation Any process that modulates the frequency, rate or extent of B cell activation. 38 0.19 3 15.97 8.96e-04
positive regulation of B cell proliferation Any process that activates or increases the rate or extent of B cell proliferation. 10 0.05 2 40.45 1.07e-03
negative regulation of cell-cell adhesion Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. 11 0.05 2 36.78 1.31e-03
regulation of cell-matrix adhesion Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix. 12 0.06 2 33.71 1.56e-03
negative regulation of cellular metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. 536 2.65 9 3.40 1.63e-03
transcription from RNA polymerase II promoter The synthesis of RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). 997 4.93 13 2.64 1.73e-03
negative regulation of cellular process Any process that stops, prevents or reduces the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. 1642 8.12 18 2.22 1.81e-03
regulation of cell-cell adhesion Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. 13 0.06 2 31.12 1.84e-03
regulation of T-helper cell differentiation Any process that modulates the frequency, rate or extent of T-helper cell differentiation. 13 0.06 2 31.12 1.84e-03
cytokine production during immune response The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. 14 0.07 2 28.90 2.14e-03
regulation of production of molecular mediator of immune response Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. 14 0.07 2 28.90 2.14e-03
regulation of cytokine production during immune response Any process that modulates the frequency, rate, or extent of cytokine production during immune response. 14 0.07 2 28.90 2.14e-03
negative regulation of biological process Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. 1697 8.39 18 2.15 2.56e-03
regulation of transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. 701 3.47 10 2.89 3.01e-03
cell activation during immune response A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. 17 0.08 2 23.80 3.16e-03
lymphocyte activation during immune response A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. 17 0.08 2 23.80 3.16e-03
T cell activation during immune response The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. 17 0.08 2 23.80 3.16e-03
T cell differentiation during immune response The process whereby an antigenically nave T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. 17 0.08 2 23.80 3.16e-03
alpha-beta T cell differentiation during immune response The process whereby an antigenically nave alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. 17 0.08 2 23.80 3.16e-03
CD4-positive, alpha-beta T cell differentiation during immune response The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. 17 0.08 2 23.80 3.16e-03
leukocyte activation during immune response A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. 17 0.08 2 23.80 3.16e-03
T-helper cell differentiation The process whereby a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. 17 0.08 2 23.80 3.16e-03
regulation of Ras GTPase activity Any process that modulates the activity of a GTPase of the Ras superfamily. 61 0.30 3 9.95 3.51e-03
regulation of isotype switching Any process that modulates the frequency, rate or extent of isotype switching. 18 0.09 2 22.47 3.55e-03
negative regulation of transcription, DNA-dependent Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription. 292 1.44 6 4.16 3.60e-03
regulation of mononuclear cell proliferation Any process that modulates the frequency, rate or extent of mononuclear cell proliferation. 62 0.31 3 9.79 3.68e-03
regulation of lymphocyte proliferation Any process that modulates the frequency, rate or extent of lymphocyte proliferation. 62 0.31 3 9.79 3.68e-03
CD4-positive, alpha beta T cell differentiation The process whereby a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell. 19 0.09 2 21.29 3.95e-03
negative regulation of metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. 615 3.04 9 2.96 4.04e-03
negative regulation of immune system process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. 20 0.10 2 20.23 4.38e-03
regulation of immune effector process Any process that modulates the frequency, rate, or extent of an immune effector process. 20 0.10 2 20.23 4.38e-03
T-helper 2 type immune response An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is typically orchestrated by the production of particular cytokines by T-helper 2 cells, most notably IL-4, IL-5, IL-10, and IL-13, resulting in enhanced production of certain antibody isotypes and other effects. 20 0.10 2 20.23 4.38e-03
negative regulation of immune response Any process that stops, prevents or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. 20 0.10 2 20.23 4.38e-03
regulation of a molecular function Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding. 636 3.14 9 2.86 5.00e-03
regulation of adaptive immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response. 23 0.11 2 17.59 5.77e-03
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. 23 0.11 2 17.59 5.77e-03
regulation of T cell differentiation Any process that modulates the frequency, rate or extent of T cell differentiation. 23 0.11 2 17.59 5.77e-03
regulation of defense response Any process that modulates the frequency, rate or extent of a defense response. 25 0.12 2 16.18 6.80e-03
positive regulation of locomotion Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. 25 0.12 2 16.18 6.80e-03
regulation of inflammatory response Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. 25 0.12 2 16.18 6.80e-03
positive regulation of B cell activation Any process that activates or increases the frequency, rate or extent of B cell activation. 25 0.12 2 16.18 6.80e-03
positive regulation of cell motility Any process that activates or increases the frequency, rate or extent of the movement of a cell. 25 0.12 2 16.18 6.80e-03
negative regulation of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis. 345 1.71 6 3.52 7.94e-03
negative regulation of programmed cell death Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. 347 1.72 6 3.50 8.16e-03
alpha-beta T cell differentiation The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta T cell. 28 0.14 2 14.45 8.48e-03
somatic recombination of immunoglobulin genes during immune response The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. 30 0.15 2 13.48 9.70e-03
somatic diversification of immunoglobulins during immune response The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response. 30 0.15 2 13.48 9.70e-03
immunoglobulin production during immune response The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. 30 0.15 2 13.48 9.70e-03
isotype switching The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. 30 0.15 2 13.48 9.70e-03
regulation of lymphocyte differentiation Any process that modulates the frequency, rate or extent of lymphocyte differentiation. 30 0.15 2 13.48 9.70e-03

Raw data (tab-delimited .txt)