L2L Microarray Analysis Tool
Results for A07EA.profile.ud50
| Results summary | View all lists in GO:BiolProc | View all genes in A07EA.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| negative regulation of B cell activation | Any process that stops, prevents or reduces the frequency, rate or extent of B cell activation. | 11 | 0.05 | 3 | 55.16 | 1.94e-05 |
| regulation of B cell proliferation | Any process that modulates the frequency, rate or extent of B cell proliferation. | 16 | 0.08 | 3 | 37.93 | 6.45e-05 |
| B cell proliferation | The rapid expansion of a B cell population by cell division. Follows B cell activation. | 27 | 0.13 | 3 | 22.47 | 3.23e-04 |
| negative regulation of transcription | Any process that stops, prevents or reduces the frequency, rate or extent of transcription. | 439 | 2.17 | 9 | 4.15 | 4.07e-04 |
| negative regulation of transcription from RNA polymerase II promoter | Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. | 201 | 0.99 | 6 | 6.04 | 5.46e-04 |
| negative regulation of lymphocyte activation | Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte activation. | 34 | 0.17 | 3 | 17.85 | 6.45e-04 |
| negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 478 | 2.36 | 9 | 3.81 | 7.43e-04 |
| regulation of Rho GTPase activity | Any process that modulates the activity of a GTPase of the Rho family. | 9 | 0.04 | 2 | 44.95 | 8.60e-04 |
| negative regulation of small GTPase mediated signal transduction | Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase mediated signal transduction. | 9 | 0.04 | 2 | 44.95 | 8.60e-04 |
| regulation of B cell activation | Any process that modulates the frequency, rate or extent of B cell activation. | 38 | 0.19 | 3 | 15.97 | 8.96e-04 |
| positive regulation of B cell proliferation | Any process that activates or increases the rate or extent of B cell proliferation. | 10 | 0.05 | 2 | 40.45 | 1.07e-03 |
| negative regulation of cell-cell adhesion | Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. | 11 | 0.05 | 2 | 36.78 | 1.31e-03 |
| regulation of cell-matrix adhesion | Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix. | 12 | 0.06 | 2 | 33.71 | 1.56e-03 |
| negative regulation of cellular metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. | 536 | 2.65 | 9 | 3.40 | 1.63e-03 |
| transcription from RNA polymerase II promoter | The synthesis of RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). | 997 | 4.93 | 13 | 2.64 | 1.73e-03 |
| negative regulation of cellular process | Any process that stops, prevents or reduces the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. | 1642 | 8.12 | 18 | 2.22 | 1.81e-03 |
| regulation of cell-cell adhesion | Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. | 13 | 0.06 | 2 | 31.12 | 1.84e-03 |
| regulation of T-helper cell differentiation | Any process that modulates the frequency, rate or extent of T-helper cell differentiation. | 13 | 0.06 | 2 | 31.12 | 1.84e-03 |
| cytokine production during immune response | The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. | 14 | 0.07 | 2 | 28.90 | 2.14e-03 |
| regulation of production of molecular mediator of immune response | Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. | 14 | 0.07 | 2 | 28.90 | 2.14e-03 |
| regulation of cytokine production during immune response | Any process that modulates the frequency, rate, or extent of cytokine production during immune response. | 14 | 0.07 | 2 | 28.90 | 2.14e-03 |
| negative regulation of biological process | Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. | 1697 | 8.39 | 18 | 2.15 | 2.56e-03 |
| regulation of transcription from RNA polymerase II promoter | Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. | 701 | 3.47 | 10 | 2.89 | 3.01e-03 |
| cell activation during immune response | A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| lymphocyte activation during immune response | A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| T cell activation during immune response | The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| T cell differentiation during immune response | The process whereby an antigenically nave T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| alpha-beta T cell differentiation during immune response | The process whereby an antigenically nave alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| CD4-positive, alpha-beta T cell differentiation during immune response | The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| leukocyte activation during immune response | A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| T-helper cell differentiation | The process whereby a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| regulation of Ras GTPase activity | Any process that modulates the activity of a GTPase of the Ras superfamily. | 61 | 0.30 | 3 | 9.95 | 3.51e-03 |
| regulation of isotype switching | Any process that modulates the frequency, rate or extent of isotype switching. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
| negative regulation of transcription, DNA-dependent | Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription. | 292 | 1.44 | 6 | 4.16 | 3.60e-03 |
| regulation of mononuclear cell proliferation | Any process that modulates the frequency, rate or extent of mononuclear cell proliferation. | 62 | 0.31 | 3 | 9.79 | 3.68e-03 |
| regulation of lymphocyte proliferation | Any process that modulates the frequency, rate or extent of lymphocyte proliferation. | 62 | 0.31 | 3 | 9.79 | 3.68e-03 |
| CD4-positive, alpha beta T cell differentiation | The process whereby a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell. | 19 | 0.09 | 2 | 21.29 | 3.95e-03 |
| negative regulation of metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. | 615 | 3.04 | 9 | 2.96 | 4.04e-03 |
| negative regulation of immune system process | Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
| regulation of immune effector process | Any process that modulates the frequency, rate, or extent of an immune effector process. | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
| T-helper 2 type immune response | An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is typically orchestrated by the production of particular cytokines by T-helper 2 cells, most notably IL-4, IL-5, IL-10, and IL-13, resulting in enhanced production of certain antibody isotypes and other effects. | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
| negative regulation of immune response | Any process that stops, prevents or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
| regulation of a molecular function | Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding. | 636 | 3.14 | 9 | 2.86 | 5.00e-03 |
| regulation of adaptive immune response | Any process that modulates the frequency, rate, or extent of an adaptive immune response. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. | Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
| regulation of T cell differentiation | Any process that modulates the frequency, rate or extent of T cell differentiation. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
| regulation of defense response | Any process that modulates the frequency, rate or extent of a defense response. | 25 | 0.12 | 2 | 16.18 | 6.80e-03 |
| positive regulation of locomotion | Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. | 25 | 0.12 | 2 | 16.18 | 6.80e-03 |
| regulation of inflammatory response | Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. | 25 | 0.12 | 2 | 16.18 | 6.80e-03 |
| positive regulation of B cell activation | Any process that activates or increases the frequency, rate or extent of B cell activation. | 25 | 0.12 | 2 | 16.18 | 6.80e-03 |
| positive regulation of cell motility | Any process that activates or increases the frequency, rate or extent of the movement of a cell. | 25 | 0.12 | 2 | 16.18 | 6.80e-03 |
| negative regulation of apoptosis | Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis. | 345 | 1.71 | 6 | 3.52 | 7.94e-03 |
| negative regulation of programmed cell death | Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 347 | 1.72 | 6 | 3.50 | 8.16e-03 |
| alpha-beta T cell differentiation | The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta T cell. | 28 | 0.14 | 2 | 14.45 | 8.48e-03 |
| somatic recombination of immunoglobulin genes during immune response | The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| somatic diversification of immunoglobulins during immune response | The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| immunoglobulin production during immune response | The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| isotype switching | The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| regulation of lymphocyte differentiation | Any process that modulates the frequency, rate or extent of lymphocyte differentiation. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |