L2L L2L Microarray Analysis Tool

Results for A03FA.profile.ud50

Results summary View all lists in L2L MDB View all genes in A03FA.profile.ud50
List Name Description Total
pdgf_es_dn Down-regulated by PDGF in mouse embryonic stem cells, via microarray-coupled gene-trap mutagenesis 6 0.03 2 67.42 3.62e-04
aged_mouse_hippocampus_any_up Up-regulated in the hippocampus of 16-month aged mice from any of four strains (S8, S10, SR1, B6J), versus 3-month young controls 78 0.39 4 10.37 6.37e-04
bay_pbmc_24hr_dn Down-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 268 1.32 6 4.53 2.37e-03
et743_blockstsa Normally induced by the HDACi TSA, but induction is blocked by Et-743 15 0.07 2 26.97 2.46e-03
zmpste24_ko_up Fifty genes most strongly up-regulated in liver tissue from mice deficient in the lamin-protease Zmpste24/Face1, versus wild-type controls 57 0.28 3 10.65 2.90e-03
cisplatin_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with cisplatin 23 0.11 2 17.59 5.77e-03
cancerdrugs_probcell_up Up-regulated by at least two of four cancer drugs (cisplatin, camptothecin, methotrextate and/or paclitaxel) in pro-B cells (FL5.12) 24 0.12 2 16.86 6.28e-03
methotrexate_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with methotrexate 24 0.12 2 16.86 6.28e-03
insulin_adip_insens_dn Down-regulated by insulin in murine adipocytes, and continue to respond following induction of insulin-resistance with TNFalpha treatment 25 0.12 2 16.18 6.80e-03
cox1_ko_cortex_up Up-regulated in the cerebral cortex of COX1-/- mice compared to wild-type controls. 80 0.40 3 7.59 7.48e-03
camptothecin_probcell_up Up-regulated in pro-B cells (FL5.12) following treatment with camptothecin 28 0.14 2 14.45 8.48e-03
cmv_hcmv_timecourse_10hrs_dn Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 10 hours 30 0.15 2 13.48 9.70e-03

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