Results summary | View all lists in GO:MoleFunc | View all genes in A01AB.profile.ud50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
phosphoinositide 3-kinase regulator activity | Modulates the activity of any of the phosphoinositide 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates. | 8 | 0.04 | 2 | 50.57 | 6.71e-04 |
insulin receptor substrate binding | Interacting selectively with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex. | 12 | 0.06 | 2 | 33.71 | 1.56e-03 |
3'-5'-exoribonuclease activity | Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule. | 14 | 0.07 | 2 | 28.90 | 2.14e-03 |
exoribonuclease activity | Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule. | 15 | 0.07 | 2 | 26.97 | 2.46e-03 |
exoribonuclease activity, producing 5'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. | 15 | 0.07 | 2 | 26.97 | 2.46e-03 |
insulin-like growth factor receptor binding | Interacting selectively with the insulin-like growth factor receptor. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
phosphatidylinositol binding | Interacting selectively with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
heparin binding | Interacting selectively with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha1-4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. | 131 | 0.65 | 4 | 6.18 | 4.25e-03 |
protein phosphatase binding | Interacting selectively with any protein phosphatase. | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
thyroid hormone receptor binding | Interacting selectively with a thyroid hormone receptor. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. | 25 | 0.12 | 2 | 16.18 | 6.80e-03 |
insulin receptor binding | Interacting selectively with the insulin receptor. | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |
hormone binding | Interacting selectively with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone. | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |
protein dimerization activity | The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. | 447 | 2.21 | 7 | 3.17 | 7.47e-03 |
acetylgalactosaminyltransferase activity | Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide. | 29 | 0.14 | 2 | 13.95 | 9.08e-03 |