L2L L2L Microarray Analysis Tool

Results for A01AB.profile.d50

Results summary View all lists in GO:MoleFunc View all genes in A01AB.profile.d50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
phosphoinositide 3-kinase regulator activity Modulates the activity of any of the phosphoinositide 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates. 8 0.02 2 101.14 1.69e-04
insulin receptor substrate binding Interacting selectively with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex. 12 0.03 2 67.42 3.97e-04
insulin-like growth factor receptor binding Interacting selectively with the insulin-like growth factor receptor. 18 0.04 2 44.95 9.11e-04
phosphatidylinositol binding Interacting selectively with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. 18 0.04 2 44.95 9.11e-04
protein phosphatase binding Interacting selectively with any protein phosphatase. 20 0.05 2 40.45 1.13e-03
insulin receptor binding Interacting selectively with the insulin receptor. 26 0.06 2 31.12 1.91e-03
hormone binding Interacting selectively with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone. 26 0.06 2 31.12 1.91e-03
phosphatase binding Interacting selectively with any phosphatase. 32 0.08 2 25.28 2.88e-03
protein complex binding Interacting selectively with any protein complex (a complex of two or more proteins that may include other nonprotein molecules). 147 0.36 3 8.26 6.01e-03

Raw data (tab-delimited .txt)