Results summary | View all lists in GO:MoleFunc | View all genes in A01AB.profile.d50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
phosphoinositide 3-kinase regulator activity | Modulates the activity of any of the phosphoinositide 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates. | 8 | 0.02 | 2 | 101.14 | 1.69e-04 |
insulin receptor substrate binding | Interacting selectively with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex. | 12 | 0.03 | 2 | 67.42 | 3.97e-04 |
insulin-like growth factor receptor binding | Interacting selectively with the insulin-like growth factor receptor. | 18 | 0.04 | 2 | 44.95 | 9.11e-04 |
phosphatidylinositol binding | Interacting selectively with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. | 18 | 0.04 | 2 | 44.95 | 9.11e-04 |
protein phosphatase binding | Interacting selectively with any protein phosphatase. | 20 | 0.05 | 2 | 40.45 | 1.13e-03 |
insulin receptor binding | Interacting selectively with the insulin receptor. | 26 | 0.06 | 2 | 31.12 | 1.91e-03 |
hormone binding | Interacting selectively with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone. | 26 | 0.06 | 2 | 31.12 | 1.91e-03 |
phosphatase binding | Interacting selectively with any phosphatase. | 32 | 0.08 | 2 | 25.28 | 2.88e-03 |
protein complex binding | Interacting selectively with any protein complex (a complex of two or more proteins that may include other nonprotein molecules). | 147 | 0.36 | 3 | 8.26 | 6.01e-03 |