Results summary | View all lists in L2L MDB | View all genes in R03C.profile.u50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
bay_pbmc_2hr_up | Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 606 | 1.50 | 14 | 9.35 | 7.23e-10 |
caries_pulp_up | Up-regulated in pulpal tissue from extracted carious teeth (cavities), compared to tissue from extracted healthy teeth | 410 | 1.01 | 8 | 7.89 | 1.07e-05 |
il2_pbmc_4hr_up | Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 510 | 1.26 | 8 | 6.35 | 5.00e-05 |
il2_pbmc_6hr_up | Up-regulated at 6hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 530 | 1.31 | 8 | 6.11 | 6.53e-05 |
bay_pbmc_4hr_up | Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 544 | 1.34 | 8 | 5.95 | 7.82e-05 |
dex_keratinocyte_4hr_up | Up-regulated in primary human keratinocytes at 4 hours following treatment with 0.1 microM dexamethasone | 35 | 0.09 | 3 | 34.67 | 9.32e-05 |
cmvuv-cmv_common_hcmv_6hrs_up | Up-regulated in fibroblasts at 6 hours following infection with either human cytomegalovirus (CMV) or UV-inactivated CMV | 37 | 0.09 | 3 | 32.80 | 1.10e-04 |
cmv_hcmv_6hrs_up | Up-regulated in fibroblasts at 6 hours following infection with human cytomegalovirus (CMV) | 46 | 0.11 | 3 | 26.38 | 2.12e-04 |
il2_pbmc_24hr_dn | Down-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 646 | 1.60 | 8 | 5.01 | 2.50e-04 |
cmv-uv_hcmv_6hrs_up | Up-regulated in fibroblasts at 6 hours following infection with UV-inactivated human cytomegalovirus | 226 | 0.56 | 5 | 8.95 | 2.76e-04 |
scw_joint_4hrs_up | Up-regulated in rat ankle joints 4 hrs following intra-articular injection of Streptococcal cell wall (SCW), a rat model of arthritis. | 230 | 0.57 | 5 | 8.79 | 2.99e-04 |
il2_pbmc_48hr_dn | Down-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 531 | 1.31 | 7 | 5.33 | 4.16e-04 |
h2o2_csbdiff_c1 | Stronger induction by H2O2 in CSB-null fibroblasts, compared to CSB-rescued (Table 2, cluster 1) | 58 | 0.14 | 3 | 20.92 | 4.21e-04 |
hsc_hsc_shared | Up-regulated in mouse hematopoietic stem cells from both adult bone marrow and fetal liver (Cluster ii, HSC Shared) | 270 | 0.67 | 5 | 7.49 | 6.18e-04 |
hdaci_colon_cluster8 | Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 8) | 18 | 0.04 | 2 | 44.95 | 9.11e-04 |
hsc_hsc_fetal | Up-regulated in mouse hematopoietic stem cells from fetal liver (HSC Shared + Fetal) | 303 | 0.75 | 5 | 6.68 | 1.03e-03 |
uv-cmv_unique_hcmv_6hrs_up | Up-regulated in fibroblasts at 6 hours following infection with UV-inactivated CMV, but not untreated CMV | 194 | 0.48 | 4 | 8.34 | 1.47e-03 |
insulin_adip_insens_dn | Down-regulated by insulin in murine adipocytes, and continue to respond following induction of insulin-resistance with TNFalpha treatment | 25 | 0.06 | 2 | 32.36 | 1.77e-03 |
il2_pbmc_48hr_up | Up-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 511 | 1.26 | 6 | 4.75 | 1.90e-03 |
hsc_hsc_adult | Up-regulated in mouse hematopoietic stem cells from adult bone marrow (HSC Shared + Adult) | 363 | 0.90 | 5 | 5.57 | 2.27e-03 |
calres_rhesus_dn | Downregulated in the vastus lateralis muscle of middle-aged rhesus monkeys subjected to caloric restriction since young adulthood vs. age-matched controls | 110 | 0.27 | 3 | 11.03 | 2.68e-03 |
dixoin_chloracne_pbmnc_up | Up-regulated in peripheral blood mononuclear cells of subjects who developed chloracne as a result of dioxin exposure, compared to subjects who did not. | 34 | 0.08 | 2 | 23.80 | 3.25e-03 |
uvc_high_all_up | Up-regulated at any timepoint following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (clusters b1-b4) | 34 | 0.08 | 2 | 23.80 | 3.25e-03 |
alk1_hmvec_2hr_up | Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). | 593 | 1.47 | 6 | 4.09 | 3.94e-03 |
alk1_hmvec_4hr_up | Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). | 593 | 1.47 | 6 | 4.09 | 3.94e-03 |
nab_lung_up | Up-regulated in human non-small cell lung carcinoma cell line H460 following 24-hour treatment with sodium butyrate | 38 | 0.09 | 2 | 21.29 | 4.05e-03 |
vegf_hmmec_12hrs_up | Up-regulated at 12hrs follwing VEGF treatment of human myometrial microvascular endothelial cells | 38 | 0.09 | 2 | 21.29 | 4.05e-03 |
bay_pbmc_24hr_dn | Down-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 268 | 0.66 | 4 | 6.04 | 4.68e-03 |
vegf_hmmec_all_up | Up-regulated at any timepoint follwing VEGF treatment of human myometrial microvascular endothelial cells | 147 | 0.36 | 3 | 8.26 | 6.01e-03 |
tgfb_hmvec_4hr_dn | Down-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 1321 | 3.27 | 9 | 2.76 | 6.41e-03 |
p53_brca1_up | Upregulated by expression of p53 in p53-null, brca1-null MEFs; most genes are further upregulated by simultaneous expression of BRCA1 | 49 | 0.12 | 2 | 16.51 | 6.65e-03 |
bay_pbmc_6hr_up | Up-regulated at 6 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 475 | 1.17 | 5 | 4.26 | 7.01e-03 |
reovirus_hek293_up | Up-regulated at any timepoint up to 24 hours following infection of HEK293 cells with reovirus strain T3Abney | 491 | 1.21 | 5 | 4.12 | 8.02e-03 |
il2_pbmc_24hr_up | Up-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 503 | 1.24 | 5 | 4.02 | 8.84e-03 |