L2L L2L Microarray Analysis Tool

Results for R03C.profile.u50

Results summary View all lists in L2L MDB View all genes in R03C.profile.u50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
bay_pbmc_2hr_up Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 606 1.50 14 9.35 7.23e-10
caries_pulp_up Up-regulated in pulpal tissue from extracted carious teeth (cavities), compared to tissue from extracted healthy teeth 410 1.01 8 7.89 1.07e-05
il2_pbmc_4hr_up Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 510 1.26 8 6.35 5.00e-05
il2_pbmc_6hr_up Up-regulated at 6hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 530 1.31 8 6.11 6.53e-05
bay_pbmc_4hr_up Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 544 1.34 8 5.95 7.82e-05
dex_keratinocyte_4hr_up Up-regulated in primary human keratinocytes at 4 hours following treatment with 0.1 microM dexamethasone 35 0.09 3 34.67 9.32e-05
cmvuv-cmv_common_hcmv_6hrs_up Up-regulated in fibroblasts at 6 hours following infection with either human cytomegalovirus (CMV) or UV-inactivated CMV 37 0.09 3 32.80 1.10e-04
cmv_hcmv_6hrs_up Up-regulated in fibroblasts at 6 hours following infection with human cytomegalovirus (CMV) 46 0.11 3 26.38 2.12e-04
il2_pbmc_24hr_dn Down-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 646 1.60 8 5.01 2.50e-04
cmv-uv_hcmv_6hrs_up Up-regulated in fibroblasts at 6 hours following infection with UV-inactivated human cytomegalovirus 226 0.56 5 8.95 2.76e-04
scw_joint_4hrs_up Up-regulated in rat ankle joints 4 hrs following intra-articular injection of Streptococcal cell wall (SCW), a rat model of arthritis. 230 0.57 5 8.79 2.99e-04
il2_pbmc_48hr_dn Down-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 531 1.31 7 5.33 4.16e-04
h2o2_csbdiff_c1 Stronger induction by H2O2 in CSB-null fibroblasts, compared to CSB-rescued (Table 2, cluster 1) 58 0.14 3 20.92 4.21e-04
hsc_hsc_shared Up-regulated in mouse hematopoietic stem cells from both adult bone marrow and fetal liver (Cluster ii, HSC Shared) 270 0.67 5 7.49 6.18e-04
hdaci_colon_cluster8 Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 8) 18 0.04 2 44.95 9.11e-04
hsc_hsc_fetal Up-regulated in mouse hematopoietic stem cells from fetal liver (HSC Shared + Fetal) 303 0.75 5 6.68 1.03e-03
uv-cmv_unique_hcmv_6hrs_up Up-regulated in fibroblasts at 6 hours following infection with UV-inactivated CMV, but not untreated CMV 194 0.48 4 8.34 1.47e-03
insulin_adip_insens_dn Down-regulated by insulin in murine adipocytes, and continue to respond following induction of insulin-resistance with TNFalpha treatment 25 0.06 2 32.36 1.77e-03
il2_pbmc_48hr_up Up-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 511 1.26 6 4.75 1.90e-03
hsc_hsc_adult Up-regulated in mouse hematopoietic stem cells from adult bone marrow (HSC Shared + Adult) 363 0.90 5 5.57 2.27e-03
calres_rhesus_dn Downregulated in the vastus lateralis muscle of middle-aged rhesus monkeys subjected to caloric restriction since young adulthood vs. age-matched controls 110 0.27 3 11.03 2.68e-03
dixoin_chloracne_pbmnc_up Up-regulated in peripheral blood mononuclear cells of subjects who developed chloracne as a result of dioxin exposure, compared to subjects who did not. 34 0.08 2 23.80 3.25e-03
uvc_high_all_up Up-regulated at any timepoint following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (clusters b1-b4) 34 0.08 2 23.80 3.25e-03
alk1_hmvec_2hr_up Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). 593 1.47 6 4.09 3.94e-03
alk1_hmvec_4hr_up Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). 593 1.47 6 4.09 3.94e-03
nab_lung_up Up-regulated in human non-small cell lung carcinoma cell line H460 following 24-hour treatment with sodium butyrate 38 0.09 2 21.29 4.05e-03
vegf_hmmec_12hrs_up Up-regulated at 12hrs follwing VEGF treatment of human myometrial microvascular endothelial cells 38 0.09 2 21.29 4.05e-03
bay_pbmc_24hr_dn Down-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 268 0.66 4 6.04 4.68e-03
vegf_hmmec_all_up Up-regulated at any timepoint follwing VEGF treatment of human myometrial microvascular endothelial cells 147 0.36 3 8.26 6.01e-03
tgfb_hmvec_4hr_dn Down-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. 1321 3.27 9 2.76 6.41e-03
p53_brca1_up Upregulated by expression of p53 in p53-null, brca1-null MEFs; most genes are further upregulated by simultaneous expression of BRCA1 49 0.12 2 16.51 6.65e-03
bay_pbmc_6hr_up Up-regulated at 6 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 475 1.17 5 4.26 7.01e-03
reovirus_hek293_up Up-regulated at any timepoint up to 24 hours following infection of HEK293 cells with reovirus strain T3Abney 491 1.21 5 4.12 8.02e-03
il2_pbmc_24hr_up Up-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 503 1.24 5 4.02 8.84e-03

Raw data (tab-delimited .txt)