L2L L2L Microarray Analysis Tool

Results for R01A.profile.d50

Results summary View all lists in L2L MDB View all genes in R01A.profile.d50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
calres_mouse_dn Downregulated in the gastrocnemius muscle of aged (30-month) mice subjected to caloric restriction since young adulthood vs. age-matched controls 79 0.20 4 20.48 4.84e-05
idx_tsa_dn_cluster6 Strongly down-regulated at 2 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 6) 48 0.12 3 25.28 2.40e-04
baf57_bt549_dn Down-regulated following stable re-expression of BAF57 in Bt549 breast cancer cells that lack functional BAF57 554 1.37 7 5.11 5.34e-04
hdaci_colon_cluster9 Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 9, associated with histone hyperAc) 78 0.19 3 15.56 1.00e-03
cmv_hcmv_timecourse_24hrs_dn Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 24 hours 82 0.20 3 14.80 1.16e-03
bay_pbmc_24hr_up Up-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 202 0.50 4 8.01 1.70e-03
hdaci_colon_but24hrs_up Upregulated by butyrate at 24 hrs in SW260 colon carcinoma cells 95 0.23 3 12.77 1.76e-03
bay-il2_pbmc_late_dn Down-regulated at 24-48 hours following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist, compared to recombinant IL-2. 205 0.51 4 7.89 1.80e-03
il2_pbmc_4hr_up Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 510 1.26 6 4.76 1.88e-03
cmv_all_dn Downregulated at any timepoint following infection of primary human foreskin fibroblasts with CMV 213 0.53 4 7.60 2.07e-03
ribavirin_rsv_dn Up-regulation by infection of human pulmonary epithelian cells (A549) with respiratory syncytial virus (RSV) is inhibited by the anti-viral drug ribavirin 101 0.25 3 12.02 2.10e-03
emt_up Up-regulated during the TGFbeta-induced epithelial-to-mesenchymal transition (EMT) of Ras-transformed mouse mammary epithelial (EpH4) cells (EMT is representative of late-stage tumor progression and metastasis) 105 0.26 3 11.56 2.35e-03
bay_pbmc_4hr_up Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 544 1.34 6 4.46 2.59e-03
bay_pbmc_2hr_up Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 606 1.50 6 4.01 4.37e-03
hdaci_colon_but48hrs_up Upregulated by butyrate at 48 hrs in SW260 colon carcinoma cells 135 0.33 3 8.99 4.75e-03
il1_cornea_up Upregulated in corneal fibroblasts after interleukin-1 treatment (Tables 1 and 2) 136 0.34 3 8.92 4.85e-03
cmv_24hrs_dn Downregulated at 24hrs following infection of primary human foreskin fibroblasts with CMV 140 0.35 3 8.67 5.25e-03
il2_pbmc_24hr_dn Down-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 646 1.60 6 3.76 5.91e-03
arthritis_mouse_common_up Up-regulated in joint tissue from both severely arthritic HTLV-I transgenic mice and IL-1Ra knock-out mice, versus wild-type littermate controls. 459 1.13 5 4.41 6.09e-03
bay_pbmc_48hr_up Up-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 475 1.17 5 4.26 7.01e-03
bay_pbmc_6hr_up Up-regulated at 6 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 475 1.17 5 4.26 7.01e-03
prmt5_kd_up Up-regulated by stable RNAi knock-down of PRMT5 in NIH 3T3 cells 306 0.76 4 5.29 7.41e-03
caries_pulp_high_up Highly up-regulated (>4-fold) in pulpal tissue from extracted carious teeth (cavities), compared to tissue from extracted healthy teeth 168 0.42 3 7.22 8.66e-03
il2_pbmc_48hr_up Up-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 511 1.26 5 3.96 9.41e-03

Raw data (tab-delimited .txt)