L2L L2L Microarray Analysis Tool

Results for N06D.profile.u50

Results summary View all lists in L2L MDB View all genes in N06D.profile.u50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
htert_dn Downregulated in hTERT-immortalized fibroblasts vs. non-immortalized controls 112 0.28 4 14.45 1.87e-04
p21_early_dn Down-regulated at early timepoints (4-8 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells 16 0.04 2 50.57 7.17e-04
gh_igf_chondrocytes_up Up-regulated in cultured human chondrocytes by both GH and IGF-1 17 0.04 2 47.59 8.11e-04
preadip_vs_fibro_dn Downregulated following 6hr differentiation of murine 3T3-L1 fibroblasts into preadipocytes; presumed direct transcriptional targets of differentiation cocktail of insulin, dexamethasone and isobutyl-methylxanthine 17 0.04 2 47.59 8.11e-04
scar_fibro_dn Downregulated in hypertrophic scar fibroblasts, compared to normal skin fibroblasts 17 0.04 2 47.59 8.11e-04
brca1ko_mef_up Up-regulated in mouse embryonic fibroblasts following targeted deletion of BRCA1 (exon 11) compared to wild-type MEFs 19 0.05 2 42.58 1.02e-03
ad12_48hrs_dn Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 48 hours post-infection 21 0.05 2 38.53 1.24e-03
il6_scar_fibro_dn Downregulated following IL-6 treatment in hypertrophic scar fibroblasts 22 0.05 2 36.78 1.37e-03
p21_p53_early_dn Down-regulated at early timepoints (4-8 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells, p53-dependent 23 0.06 2 35.18 1.49e-03
ad12_24hrs_dn Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 24 hours post-infection 24 0.06 2 33.71 1.63e-03
cmv_hcmv_timecourse_6hrs_dn Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 6 hours 95 0.23 3 12.77 1.76e-03
ad12_32hrs_dn Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 32 hours post-infection 27 0.07 2 29.97 2.06e-03
uvb_scc_dn Downregulated by UV-B light in squamous cell carinoma cells 219 0.54 4 7.39 2.28e-03
cmv_hcmv_6hrs_dn Down-regulated in fibroblasts at 6 hours following infection with human cytomegalovirus (CMV) 109 0.27 3 11.13 2.61e-03
vegf_huvec_30min_up Up-regulated 30 minutes after VEGF treatment in human umbilical vein endothelial cells 41 0.10 2 19.73 4.70e-03
ad12_any_dn Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at any timepoint to 48 hrs hours post-infection 42 0.10 2 19.26 4.93e-03
prmt5_kd_dn Down-regulated by stable RNAi knock-down of PRMT5 in NIH 3T3 cells 45 0.11 2 17.98 5.64e-03
o6bg_resist_medulloblastoma_up Up-regulated in a medulloblastoma cell line resistant to both BCNU and O6-BG, compared to sensitive parent line (D-341 MED) 46 0.11 2 17.59 5.88e-03
p21_any_dn Down-regulated at any timepoint (4-24 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells 50 0.12 2 16.18 6.92e-03
adipogenesis_hmsc_class8_dn Down-regulated 1-14 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class VIII) 59 0.15 2 13.71 9.52e-03

Raw data (tab-delimited .txt)