Results summary | View all lists in L2L MDB | View all genes in N06D.profile.u50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
htert_dn | Downregulated in hTERT-immortalized fibroblasts vs. non-immortalized controls | 112 | 0.28 | 4 | 14.45 | 1.87e-04 |
p21_early_dn | Down-regulated at early timepoints (4-8 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells | 16 | 0.04 | 2 | 50.57 | 7.17e-04 |
gh_igf_chondrocytes_up | Up-regulated in cultured human chondrocytes by both GH and IGF-1 | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
preadip_vs_fibro_dn | Downregulated following 6hr differentiation of murine 3T3-L1 fibroblasts into preadipocytes; presumed direct transcriptional targets of differentiation cocktail of insulin, dexamethasone and isobutyl-methylxanthine | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
scar_fibro_dn | Downregulated in hypertrophic scar fibroblasts, compared to normal skin fibroblasts | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
brca1ko_mef_up | Up-regulated in mouse embryonic fibroblasts following targeted deletion of BRCA1 (exon 11) compared to wild-type MEFs | 19 | 0.05 | 2 | 42.58 | 1.02e-03 |
ad12_48hrs_dn | Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 48 hours post-infection | 21 | 0.05 | 2 | 38.53 | 1.24e-03 |
il6_scar_fibro_dn | Downregulated following IL-6 treatment in hypertrophic scar fibroblasts | 22 | 0.05 | 2 | 36.78 | 1.37e-03 |
p21_p53_early_dn | Down-regulated at early timepoints (4-8 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells, p53-dependent | 23 | 0.06 | 2 | 35.18 | 1.49e-03 |
ad12_24hrs_dn | Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 24 hours post-infection | 24 | 0.06 | 2 | 33.71 | 1.63e-03 |
cmv_hcmv_timecourse_6hrs_dn | Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 6 hours | 95 | 0.23 | 3 | 12.77 | 1.76e-03 |
ad12_32hrs_dn | Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 32 hours post-infection | 27 | 0.07 | 2 | 29.97 | 2.06e-03 |
uvb_scc_dn | Downregulated by UV-B light in squamous cell carinoma cells | 219 | 0.54 | 4 | 7.39 | 2.28e-03 |
cmv_hcmv_6hrs_dn | Down-regulated in fibroblasts at 6 hours following infection with human cytomegalovirus (CMV) | 109 | 0.27 | 3 | 11.13 | 2.61e-03 |
vegf_huvec_30min_up | Up-regulated 30 minutes after VEGF treatment in human umbilical vein endothelial cells | 41 | 0.10 | 2 | 19.73 | 4.70e-03 |
ad12_any_dn | Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at any timepoint to 48 hrs hours post-infection | 42 | 0.10 | 2 | 19.26 | 4.93e-03 |
prmt5_kd_dn | Down-regulated by stable RNAi knock-down of PRMT5 in NIH 3T3 cells | 45 | 0.11 | 2 | 17.98 | 5.64e-03 |
o6bg_resist_medulloblastoma_up | Up-regulated in a medulloblastoma cell line resistant to both BCNU and O6-BG, compared to sensitive parent line (D-341 MED) | 46 | 0.11 | 2 | 17.59 | 5.88e-03 |
p21_any_dn | Down-regulated at any timepoint (4-24 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells | 50 | 0.12 | 2 | 16.18 | 6.92e-03 |
adipogenesis_hmsc_class8_dn | Down-regulated 1-14 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class VIII) | 59 | 0.15 | 2 | 13.71 | 9.52e-03 |