L2L Microarray Analysis Tool
Results for N06A.profile.d50
| Results summary | View all lists in GO:BiolProc | View all genes in N06A.profile.d50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| ribonucleoprotein complex biogenesis and assembly | The cellular process by which a complex containing RNA and proteins, is synthesized, aggregates, and bonds together. | 239 | 0.59 | 9 | 15.23 | 1.24e-08 |
| ribosome biogenesis and assembly | The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis. | 89 | 0.22 | 6 | 27.27 | 1.11e-07 |
| DNA recombination | The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. | 158 | 0.39 | 6 | 15.36 | 3.25e-06 |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 4320 | 10.68 | 27 | 2.53 | 1.93e-05 |
| RNA processing | Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. | 622 | 1.54 | 9 | 5.85 | 3.22e-05 |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. | 77 | 0.19 | 4 | 21.02 | 4.37e-05 |
| rRNA metabolic process | The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes. | 78 | 0.19 | 4 | 20.75 | 4.60e-05 |
| M phase | Progression through M phase, the part of the cell cycle comprising nuclear division and cytokinesis. | 375 | 0.93 | 7 | 7.55 | 5.00e-05 |
| DNA replication | The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. | 277 | 0.68 | 6 | 8.76 | 7.66e-05 |
| response to DNA damage stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. | 412 | 1.02 | 7 | 6.87 | 8.97e-05 |
| mitotic checkpoint | A signal transduction-based surveillance mechanism that ensures accurate chromosome segregation by preventing entry into, passage through and exit from mitosis. Events that may be monitored include the formation of a correctly assembled spindle, the position of the spindle pole (centrosome) and the orientation of the spindle and cellular morphogenesis. | 37 | 0.09 | 3 | 32.80 | 1.10e-04 |
| response to endogenous stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endogenous stimulus. | 453 | 1.12 | 7 | 6.25 | 1.60e-04 |
| cell cycle process | A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. | 1144 | 2.83 | 11 | 3.89 | 1.73e-04 |
| cell cycle checkpoint | A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. | 112 | 0.28 | 4 | 14.45 | 1.87e-04 |
| cell cycle phase | A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. | 474 | 1.17 | 7 | 5.97 | 2.11e-04 |
| G2/M transition DNA damage checkpoint | A cell cycle checkpoint that blocks cell cycle progression from G2 to M phase in response to DNA damage. | 11 | 0.03 | 2 | 73.55 | 3.31e-04 |
| G2/M transition checkpoint | Any cell cycle checkpoint that blocks entry into M phase. | 11 | 0.03 | 2 | 73.55 | 3.31e-04 |
| mRNA processing | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. | 382 | 0.94 | 6 | 6.35 | 4.29e-04 |
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. | 1307 | 3.23 | 11 | 3.40 | 5.26e-04 |
| RNA catabolic process | The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. | 64 | 0.16 | 3 | 18.96 | 5.62e-04 |
| regulation of cyclin-dependent protein kinase activity | Any process that modulates the frequency, rate or extent of CDK activity. | 65 | 0.16 | 3 | 18.67 | 5.88e-04 |
| DNA metabolic process | The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. | 922 | 2.28 | 9 | 3.95 | 5.89e-04 |
| pyrimidine ribonucleotide biosynthetic process | The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. | 16 | 0.04 | 2 | 50.57 | 7.17e-04 |
| mitosis | Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. | 284 | 0.70 | 5 | 7.12 | 7.75e-04 |
| transcription from RNA polymerase I promoter | The synthesis of RNA from a DNA template by RNA polymerase I (Pol I), originating at a Pol I-specific promoter. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
| M phase of mitotic cell cycle | Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place. | 290 | 0.72 | 5 | 6.97 | 8.51e-04 |
| pyrimidine ribonucleotide metabolic process | The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. | 18 | 0.04 | 2 | 44.95 | 9.11e-04 |
| mRNA metabolic process | The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. | 453 | 1.12 | 6 | 5.36 | 1.04e-03 |
| translational initiation | The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. | 79 | 0.20 | 3 | 15.36 | 1.04e-03 |
| pyrimidine nucleotide biosynthetic process | The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. | 21 | 0.05 | 2 | 38.53 | 1.24e-03 |
| DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. | 325 | 0.80 | 5 | 6.22 | 1.41e-03 |
| regulation of mitosis | Any process that modulates the frequency, rate or extent of mitosis. | 91 | 0.22 | 3 | 13.34 | 1.56e-03 |
| regulation of progression through cell cycle | Any process that modulates the rate or extent of progression through the cell cycle. | 875 | 2.16 | 8 | 3.70 | 1.75e-03 |
| regulation of cell cycle | A cell cycle process that modulates the rate, extent or mode of the cell cycle. | 880 | 2.18 | 8 | 3.68 | 1.81e-03 |
| RNA splicing | The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. | 347 | 0.86 | 5 | 5.83 | 1.87e-03 |
| meiosis | Progression through meiosis, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiosis occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations. | 97 | 0.24 | 3 | 12.51 | 1.87e-03 |
| M phase of meiotic cell cycle | Progression through M phase, the part of the meiotic cell cycle during which meiosis and cytokinesis take place. | 97 | 0.24 | 3 | 12.51 | 1.87e-03 |
| meiotic cell cycle | Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell. | 98 | 0.24 | 3 | 12.38 | 1.93e-03 |
| mRNA catabolic process, nonsense-mediated decay | The nonsense-mediated mRNA decay pathway degrades mRNAs transcribed from genes in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
| RNA metabolic process | The chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. | 3263 | 8.07 | 17 | 2.11 | 3.98e-03 |
| mitotic cell cycle | Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, in which a cell is duplicated without changing ploidy; comprises four successive phases called G1, S, G2, and M. | 421 | 1.04 | 5 | 4.80 | 4.26e-03 |
| pyrimidine nucleotide metabolic process | The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. | 39 | 0.10 | 2 | 20.75 | 4.26e-03 |
| mRNA catabolic process | The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. | 41 | 0.10 | 2 | 19.73 | 4.70e-03 |
| DNA-dependent DNA replication | The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. | 140 | 0.35 | 3 | 8.67 | 5.25e-03 |
| DNA replication initiation | The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action. | 44 | 0.11 | 2 | 18.39 | 5.40e-03 |
| regulation of translational initiation | Any process that modulates the frequency, rate or extent of translational initiation. | 48 | 0.12 | 2 | 16.86 | 6.39e-03 |
| cell division | The processes resulting in the physical partitioning and separation of a cell into daughter cells. | 297 | 0.73 | 4 | 5.45 | 6.69e-03 |
| biopolymer metabolic process | The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. | 5812 | 14.37 | 25 | 1.74 | 6.76e-03 |
| protein-RNA complex assembly | The aggregation and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. | 154 | 0.38 | 3 | 7.88 | 6.83e-03 |
| metabolic process | Processes that cause many of the chemical changes in living organisms, including anabolism and catabolism. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. | 9690 | 23.95 | 37 | 1.54 | 7.91e-03 |
| DNA damage checkpoint | A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds. | 57 | 0.14 | 2 | 14.19 | 8.91e-03 |