L2L L2L Microarray Analysis Tool

Results for L02B.profile.u50

Results summary View all lists in L2L MDB View all genes in L02B.profile.u50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
aom-dss_colon_5wks_up Up-regulated in mouse colonic mucosa after 5 weeks of treatment with the colon carcinogens azoxymethane (AOM) and 2% dextran sodium sulfate (DSS) vs. untreated controls. 133 0.33 4 12.17 3.61e-04
mmc_res_xenografts_up Up-regulation is correlated with resistance of human cancer xenografts to mitomycin C 14 0.03 2 57.79 5.45e-04
dixoin_pbmnc_up Up-regulated in peripheral blood mononuclear cells of subjects with high exposure to dioxin, compared to low-exposure controls. 17 0.04 2 47.59 8.11e-04
cmv_hcmv_timecourse_1hr_dn Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 1 hour 73 0.18 3 16.62 8.25e-04
5fu_resist_gastric_dn Downregulated in gastric cancer cell lines reistant to 5-fluorouracil, compared to parent chemosensitive lines 30 0.07 2 26.97 2.54e-03
dex_keratinocyte_4hr_up Up-regulated in primary human keratinocytes at 4 hours following treatment with 0.1 microM dexamethasone 35 0.09 2 23.12 3.44e-03
gh_exogenous_any_dn Down-regulated at any time point (1-24 hours) following treatment of mammary carcinoma cells (MCF-7) with exogenous human growth hormone 142 0.35 3 8.55 5.46e-03
uv-4nqo_fibro_dn Down-regulated at any timepoint by treatment of human fibroblasts with UV light or 4-NQO, but not by gamma radiation 48 0.12 2 16.86 6.39e-03
igf_vs_pdgf_dn Down-regulated in mouse C2AS12 myoblasts by treatment with IGF1, compared to treatment with PDGF 53 0.13 2 15.27 7.74e-03
hdaci_colon_but12hrs_up Upregulated by butyrate at 12 hrs in SW260 colon carcinoma cells 54 0.13 2 14.98 8.03e-03
bap_hepg2_dn Down-regulated at least 1.4-fold following treatment of HepG2 human hepatocellular carcinoma cells with carcinogen benzo(a)pyrene (BaP), at any time point from 6-48 hours and at any concentration from 0.25-5 microM. 56 0.14 2 14.45 8.61e-03

Raw data (tab-delimited .txt)