Results summary | View all lists in L2L MDB | View all genes in L01X.profile.d50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
uvc_xpcs_all_dn | Down-regulated at any timepoint following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC | 1048 | 2.59 | 14 | 5.40 | 6.00e-07 |
uvc_xpcs_8hr_dn | Down-regulated at 8 hours following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC | 911 | 2.25 | 11 | 4.88 | 2.35e-05 |
uvc_ttd_all_dn | Down-regulated at any timepoint following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 780 | 1.93 | 10 | 5.19 | 3.31e-05 |
dox_resist_gastric_up | Upregulated in gastric cancer cell lines reistant to doxorubicin, compared to parent chemosensitive lines | 74 | 0.18 | 4 | 21.87 | 3.74e-05 |
uvc_ttd_4hr_dn | Down-regulated at 4 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 641 | 1.58 | 9 | 5.68 | 4.06e-05 |
heatshock_hela_4hr_dn | Down-regulated at 4 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05). | 1829 | 4.52 | 14 | 3.10 | 2.58e-04 |
p21_any_dn | Down-regulated at any timepoint (4-24 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells | 50 | 0.12 | 3 | 24.27 | 2.71e-04 |
hsc_lthsc_adult | Up-regulated in mouse long-term functional hematopoietic stem cells from adult bone marrow (LT-HSC Shared + Adult) | 385 | 0.95 | 6 | 6.30 | 4.47e-04 |
uvb_nhek1_c6 | Downregulated by UV-B light in normal human epidermal keratinocytes, cluster 6 | 268 | 0.66 | 5 | 7.55 | 5.98e-04 |
nf90_dn | Downregulated by ectopic expression of NF90 in GHOST(3)CXCR4 cells | 66 | 0.16 | 3 | 18.39 | 6.15e-04 |
hsc_lthsc_fetal | Up-regulated in mouse long-term functional hematopoietic stem cells from fetal liver (LT-HSC Shared) | 272 | 0.67 | 5 | 7.44 | 6.39e-04 |
hsc_lthsc_shared | Up-regulated in mouse long-term functional hematopoietic stem cells from both adult bone marrow and fetal liver (Cluster i, LT-HSC Shared) | 272 | 0.67 | 5 | 7.44 | 6.39e-04 |
p21_early_dn | Down-regulated at early timepoints (4-8 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells | 16 | 0.04 | 2 | 50.57 | 7.17e-04 |
middleage_dn | Downregulated in fibroblasts from middle-age individuals, compared to young | 23 | 0.06 | 2 | 35.18 | 1.49e-03 |
uvc_ttd-xpcs_common_dn | Down-regulated at any timepoint following treatment of both XPB/CS and XPB/TTD fibroblasts with 3 J/m^2 UVC | 344 | 0.85 | 5 | 5.88 | 1.80e-03 |
uvc_xpcs_4hr_dn | Down-regulated at 4 hours following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC | 519 | 1.28 | 6 | 4.68 | 2.05e-03 |
insulin_adip_sens_dn | Down-regulated by insulin in murine adipocytes, but response is blunted following induction of insulin-resistance with TNFalpha treatment | 29 | 0.07 | 2 | 27.90 | 2.37e-03 |
uvb_nhek1_dn | Downregulated by UV-B light in normal human epidermal keratinocytes | 542 | 1.34 | 6 | 4.48 | 2.54e-03 |
dox_resist_gastric_dn | Downregulated in gastric cancer cell lines reistant to doxorubicin, compared to parent chemosensitive lines | 43 | 0.11 | 2 | 18.82 | 5.16e-03 |
brca_er_pos | Genes whose expression is consistently positively correlated with estrogen receptor status in breast cancer - higher expression is associated with ER-positive tumors | 842 | 2.08 | 7 | 3.36 | 5.53e-03 |
pod1_ko_dn | Down-regulated in glomeruli isolated from Pod1 knockout mice, versus wild-type controls | 1135 | 2.81 | 8 | 2.85 | 8.14e-03 |