L2L L2L Microarray Analysis Tool

Results for J02A.profile.u50

Results summary View all lists in L2L MDB View all genes in J02A.profile.u50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
ad12_any_up Up-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at any timepoint to 48 hrs hours post-infection 15 0.04 2 53.94 6.28e-04
brca1_overexp_prostate_up Up-regulated with stable, ectopic overexpression of BRCA1 in DU-145 human prostate cancer cell lines, compared to neo-only controls 308 0.76 5 6.57 1.11e-03
cmv_hcmv_timecourse_4hrs_up Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 4 hours 26 0.06 2 31.12 1.91e-03
5fu_resist_gastric_dn Downregulated in gastric cancer cell lines reistant to 5-fluorouracil, compared to parent chemosensitive lines 30 0.07 2 26.97 2.54e-03
but_tsa_up Upregulated by the combination of TSA and butyrate in HT-29 cells 36 0.09 2 22.47 3.64e-03
bap_mcf7_dn Down-regulated at least 1.4-fold following treatment of MCF-7 human breast carcinoma cells with carcinogen benzo(a)pyrene (BaP), at any time point from 6-48 hours and at any concentration from 0.25-5 microM. 135 0.33 3 8.99 4.75e-03
dox_resist_gastric_dn Downregulated in gastric cancer cell lines reistant to doxorubicin, compared to parent chemosensitive lines 43 0.11 2 18.82 5.16e-03
idx_tsa_up_cluster1 Strongly up-regulated at 2 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 1) 44 0.11 2 18.39 5.40e-03
camptothecin_probcell_dn Down-regulated in pro-B cells (FL5.12) following treatment with camptothecin 52 0.13 2 15.56 7.46e-03
vegf_huvec_2hrs_up Up-regulated 2 hours after VEGF treatment in human umbilical vein endothelial cells 54 0.13 2 14.98 8.03e-03
hdaci_colon_but48hrs_dn Downregulated by butyrate at 48 hrs in SW260 colon carcinoma cells 165 0.41 3 7.36 8.25e-03
serum_fibroblast_core_dn Core group of genes consistently down-regulated following exposure to serum in a variety of human fibroblast cell lines (higher expression in quiescent cells, not cell-cycle dependent) 319 0.79 4 5.07 8.55e-03
il2_pbmc_48hr_up Up-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. 511 1.26 5 3.96 9.41e-03

Raw data (tab-delimited .txt)