L2L Microarray Analysis Tool
Results for D10A.profile.ud50
| Results summary | View all lists in L2L MDB | View all genes in D10A.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| dex_keratinocyte_1hr_dn | Down-regulated in primary human keratinocytes at 1 hour following treatment with 0.1 microM dexamethasone | 24 | 0.12 | 4 | 33.71 | 5.87e-06 |
| lvad_heartfailure_up | Upregulated in the left ventricle myocardium of patients with heart failure following implantation of a left ventricular assist device | 180 | 0.89 | 6 | 6.74 | 3.05e-04 |
| myod_nih3t3_up | Up-regulated at 24 hours in NIH 3T3 murine fibroblasts following transduction with MyoD and incubation in differentiation medium | 134 | 0.66 | 5 | 7.55 | 5.81e-04 |
| uvc_ttd_all_dn | Down-regulated at any timepoint following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 780 | 3.86 | 12 | 3.11 | 6.45e-04 |
| hypoxia_reg_up | Upregulated by hypoxia in renal cells, and downregulated with reoxygenation | 80 | 0.40 | 4 | 10.11 | 7.00e-04 |
| myod_brg1_up | Genes up-regulated following transduction of MyoD in NIH 3T3 cells that fail to acheive full induction with expression of a dominant-negative BRG1 allele; induction thought to require functional BRG1 | 40 | 0.20 | 3 | 15.17 | 1.04e-03 |
| emt_dn | Down-regulated during the TGFbeta-induced epithelial-to-mesenchymal transition (EMT) of Ras-transformed mouse mammary epithelial (EpH4) cells (EMT is representative of late-stage tumor progression and metastasis) | 89 | 0.44 | 4 | 9.09 | 1.04e-03 |
| mouse_tissue_placenta | Genes expressed specifically in mouse placenta tissue | 12 | 0.06 | 2 | 33.71 | 1.56e-03 |
| uvc_ttd_4hr_dn | Down-regulated at 4 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 641 | 3.17 | 10 | 3.16 | 1.59e-03 |
| oldonly_fibro_up | Upregulated in fibroblasts from old (but not Werner) individuals, compared to young | 54 | 0.27 | 3 | 11.24 | 2.48e-03 |
| uvc_ttd_8hr_dn | Down-regulated at 8 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 382 | 1.89 | 7 | 3.71 | 3.24e-03 |
| parp_ko_up | Upregulated in MEF cells from PARP knockout mice | 61 | 0.30 | 3 | 9.95 | 3.51e-03 |
| ni2_mouse_up | Upregulated by nickel(II) in sensitive A/J mouse lung tissue | 65 | 0.32 | 3 | 9.34 | 4.20e-03 |
| tnfalpha_30min_up | Upregulated 30min after TNF-alpha treatment of HeLa cells | 68 | 0.34 | 3 | 8.92 | 4.77e-03 |
| stemcell_hematopoietic_up | Enriched in mouse hematopoietic stem cells, compared to differentiated brain and bone marrow cells | 2092 | 10.34 | 20 | 1.93 | 4.84e-03 |
| dex_keratinocyte_4hr_dn | Down-regulated in primary human keratinocytes at 4 hours following treatment with 0.1 microM dexamethasone | 69 | 0.34 | 3 | 8.79 | 4.96e-03 |
| alzheimers_incipient_up | Upregulated in correlation with incipient Alzheimer's Disease, in the CA1 region of the hippocampus | 754 | 3.73 | 10 | 2.68 | 4.98e-03 |
| tnfalpha_adip_up | Upregulated in mature, differentiated adipocytes following treatment with TNFalpha | 22 | 0.11 | 2 | 18.39 | 5.29e-03 |
| et743pt650_colonca_dn | Downregulated by both Et-743 and Pt-650 in HCT116 cells (Fig. 6 A) | 76 | 0.38 | 3 | 7.98 | 6.49e-03 |
| hdaci_colon_cluster9 | Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 9, associated with histone hyperAc) | 78 | 0.39 | 3 | 7.78 | 6.98e-03 |
| bay_pbmc_30min_up | up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 82 | 0.41 | 3 | 7.40 | 8.00e-03 |
| old_fibro_up | Upregulated in fibroblasts from old individuals, compared to young | 84 | 0.42 | 3 | 7.22 | 8.55e-03 |