L2L Microarray Analysis Tool
Results for D10A.profile.u50
| Results summary | View all lists in L2L MDB | View all genes in D10A.profile.u50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| dex_keratinocyte_1hr_dn | Down-regulated in primary human keratinocytes at 1 hour following treatment with 0.1 microM dexamethasone | 24 | 0.06 | 4 | 67.42 | 3.81e-07 |
| lvad_heartfailure_up | Upregulated in the left ventricle myocardium of patients with heart failure following implantation of a left ventricular assist device | 180 | 0.44 | 6 | 13.48 | 6.86e-06 |
| emt_dn | Down-regulated during the TGFbeta-induced epithelial-to-mesenchymal transition (EMT) of Ras-transformed mouse mammary epithelial (EpH4) cells (EMT is representative of late-stage tumor progression and metastasis) | 89 | 0.22 | 4 | 18.18 | 7.71e-05 |
| mouse_tissue_placenta | Genes expressed specifically in mouse placenta tissue | 12 | 0.03 | 2 | 67.42 | 3.97e-04 |
| ni2_mouse_up | Upregulated by nickel(II) in sensitive A/J mouse lung tissue | 65 | 0.16 | 3 | 18.67 | 5.88e-04 |
| alzheimers_incipient_up | Upregulated in correlation with incipient Alzheimer's Disease, in the CA1 region of the hippocampus | 754 | 1.86 | 8 | 4.29 | 6.87e-04 |
| dex_keratinocyte_4hr_dn | Down-regulated in primary human keratinocytes at 4 hours following treatment with 0.1 microM dexamethasone | 69 | 0.17 | 3 | 17.59 | 7.01e-04 |
| hypoxia_reg_up | Upregulated by hypoxia in renal cells, and downregulated with reoxygenation | 80 | 0.20 | 3 | 15.17 | 1.08e-03 |
| tnfalpha_adip_up | Upregulated in mature, differentiated adipocytes following treatment with TNFalpha | 22 | 0.05 | 2 | 36.78 | 1.37e-03 |
| bay_pbmc_2hr_up | Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 606 | 1.50 | 6 | 4.01 | 4.37e-03 |
| wnt3a_mammary_up | Up-regulated in normal mouse mammary gland cells following treatment with Wnt3A (top 124 genes). | 133 | 0.33 | 3 | 9.12 | 4.56e-03 |
| myod_nih3t3_up | Up-regulated at 24 hours in NIH 3T3 murine fibroblasts following transduction with MyoD and incubation in differentiation medium | 134 | 0.33 | 3 | 9.06 | 4.65e-03 |
| xpb_ttd-cs_dn | Down-regulated in XPB/TTD fibroblasts (expressing XPB-A355C), compared to XPB/CS fibroblasts (expressing XPB-T296C) | 41 | 0.10 | 2 | 19.73 | 4.70e-03 |
| alzheimers_disease_up | Upregulated in correlation with overt Alzheimer's Disease, in the CA1 region of the hippocampus | 3137 | 7.75 | 16 | 2.06 | 6.18e-03 |
| adip_human_dn | Down-regulated in primary human adipocytes, versus preadipocytes | 52 | 0.13 | 2 | 15.56 | 7.46e-03 |
| il2_pbmc_24hr_up | Up-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 503 | 1.24 | 5 | 4.02 | 8.84e-03 |