L2L Microarray Analysis Tool
Results for D07X.profile.ud50
| Results summary | View all lists in GO:BiolProc | View all genes in D07X.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| negative regulation of cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation. | 90 | 0.44 | 5 | 11.24 | 9.16e-05 |
| transcription from RNA polymerase II promoter | The synthesis of RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). | 997 | 4.93 | 15 | 3.04 | 1.86e-04 |
| negative regulation of developmental process | Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). | 110 | 0.54 | 5 | 9.19 | 2.35e-04 |
| regulation of transcription from RNA polymerase II promoter | Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. | 701 | 3.47 | 12 | 3.46 | 2.52e-04 |
| negative regulation of biological process | Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. | 1697 | 8.39 | 20 | 2.38 | 4.39e-04 |
| cell differentiation | The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate. | 2359 | 11.66 | 25 | 2.14 | 4.44e-04 |
| cellular developmental process | A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. | 2359 | 11.66 | 25 | 2.14 | 4.44e-04 |
| regulation of interleukin-6 biosynthetic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6. | 8 | 0.04 | 2 | 50.57 | 6.71e-04 |
| negative regulation of cellular process | Any process that stops, prevents or reduces the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. | 1642 | 8.12 | 19 | 2.34 | 7.44e-04 |
| developmental process | A biological process whose specific outcome is the progression of an integrated living unit: a cell, tissue, organ, or organism over time from an initial condition to a later condition. | 4255 | 21.04 | 37 | 1.76 | 9.95e-04 |
| interleukin-6 production | The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. | 10 | 0.05 | 2 | 40.45 | 1.07e-03 |
| interleukin-6 biosynthetic process | The chemical reactions and pathways resulting in the formation of interleukin-6. | 10 | 0.05 | 2 | 40.45 | 1.07e-03 |
| negative regulation of cellular metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. | 536 | 2.65 | 9 | 3.40 | 1.63e-03 |
| cell death | The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. | 1152 | 5.70 | 14 | 2.46 | 2.24e-03 |
| death | A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. | 1152 | 5.70 | 14 | 2.46 | 2.24e-03 |
| brain development | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). | 183 | 0.90 | 5 | 5.53 | 2.31e-03 |
| negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 478 | 2.36 | 8 | 3.39 | 2.96e-03 |
| organ development | Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. | 1733 | 8.57 | 18 | 2.10 | 3.18e-03 |
| multicellular organismal development | The biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). | 3036 | 15.01 | 27 | 1.80 | 3.26e-03 |
| negative regulation of metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. | 615 | 3.04 | 9 | 2.96 | 4.04e-03 |
| response to metal ion | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. | 21 | 0.10 | 2 | 19.26 | 4.82e-03 |
| cell development | The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. | 1692 | 8.37 | 17 | 2.03 | 5.57e-03 |
| regulation of actin filament length | Any process that controls the length of actin filaments in a cell. | 73 | 0.36 | 3 | 8.31 | 5.81e-03 |
| regulation of cell differentiation | Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features. | 233 | 1.15 | 5 | 4.34 | 6.40e-03 |
| central nervous system development | The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. | 332 | 1.64 | 6 | 3.66 | 6.64e-03 |
| negative regulation of transcription | Any process that stops, prevents or reduces the frequency, rate or extent of transcription. | 439 | 2.17 | 7 | 3.23 | 6.80e-03 |
| nervous system development | The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. | 1045 | 5.17 | 12 | 2.32 | 6.82e-03 |
| multicellular organismal process | The biological processes, occurring at the level of the organism, pertinent to the function of the organism. | 4325 | 21.38 | 34 | 1.59 | 6.98e-03 |
| response to inorganic substance | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. | 27 | 0.13 | 2 | 14.98 | 7.90e-03 |
| negative regulation of myeloid cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of myeloid cell differentiation. | 27 | 0.13 | 2 | 14.98 | 7.90e-03 |
| regulation of transcription, DNA-dependent | Any process that modulates the frequency, rate or extent of DNA-dependent transcription. | 2510 | 12.41 | 22 | 1.77 | 8.55e-03 |
| apoptosis | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. | 1078 | 5.33 | 12 | 2.25 | 8.59e-03 |
| system development | The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. | 2362 | 11.68 | 21 | 1.80 | 8.64e-03 |
| programmed cell death | Cell death resulting from activation of endogenous cellular processes. | 1086 | 5.37 | 12 | 2.24 | 9.07e-03 |