L2L L2L Microarray Analysis Tool

Results for C03D.profile.ud50

Results summary View all lists in L2L MDB View all genes in C03D.profile.ud50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
heatshock_hela_2hr_dn Down-regulated at 2 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05). 223 1.10 6 5.44 9.36e-04
heatshock_hela_4hr_dn Down-regulated at 4 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05). 1829 9.04 20 2.21 1.08e-03
et743_sarcoma_24hrs_dn Down-regulated at 24 hours following treatment with Et-743 in at least 8 of 11 sarcoma cell lines 163 0.81 5 6.20 1.40e-03
dac_cgi_fibro_dn Downregulated by DAC treatment in LD419 fibroblast cells, with 5' CpG island 12 0.06 2 33.71 1.56e-03
rcc_nl_up Upregulated in VHL-rescued renal carcinoma vs. normal renal cells (Fig. 2d+e) 899 4.44 12 2.70 2.11e-03
5azac_hepg2_dn Down-regulated in human hepatoma cells (HepG2) following 48 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC). 1830 9.05 19 2.10 2.50e-03
oxstress_breastca_dn Downregulated by H2O2, Menadione and t-BH in breast cancer cells 16 0.08 2 25.28 2.80e-03
dac_fibro_dn Downregulated by DAC treatment in LD419 fibroblast cells 17 0.08 2 23.80 3.16e-03
tsadac_hypometh_hyperac_ovca_up Genes with basally hypomethylated promoters upregulated by the combination of TSA and DAC in ovarian carcinoma (CP70) cells, with hyperacetylated promoters upon activation 17 0.08 2 23.80 3.16e-03
serum_fibroblast_cellcycle Cell-cycle dependent genes regulated following exposure to serum in a variety of human fibroblast cell lines 197 0.97 5 5.13 3.17e-03
17aag_ovca_dn Down-regulated 24 hours following treatment of human ovarian cancer cells (A2780) with the HSP90 inhibitor 17AAG (60 nM) 129 0.64 4 6.27 4.03e-03
tsa_hepg2_dn Down-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 500 nM trichostatin A (TSA). 1237 6.12 14 2.29 4.17e-03
et743_sarcoma_48hrs_dn Down-regulated at48 hours following treatment with Et-743 in at least 8 of 11 sarcoma cell lines 304 1.50 6 3.99 4.38e-03
adip_diff_cluster5 Strongly upregulated at 24 hours during differentiation of 3T3-L1 fibroblasts into adipocytes (cluster 5) 67 0.33 3 9.06 4.57e-03
tsadac_hypometh_ovca_up Genes with basally hypomethylated promoters upregulated by the combination of TSA and DAC in ovarian carcinoma (CP70) cells 70 0.35 3 8.67 5.17e-03
middleage_dn Downregulated in fibroblasts from middle-age individuals, compared to young 23 0.11 2 17.59 5.77e-03
p21_p53_early_dn Down-regulated at early timepoints (4-8 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells, p53-dependent 23 0.11 2 17.59 5.77e-03
cmv_hcmv_timecourse_14hrs_up Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 14 hours 84 0.42 3 7.22 8.55e-03
h2o2_csbrescued_c1_up Upregulated by H2O2 in CSB-rescued fibroblasts (Table 1, cluster 1) 84 0.42 3 7.22 8.55e-03
et743_sarcoma_dn Down-regulated following treatment with Et-743 at any timepoint in at least 8 of 11 sarcoma cell lines 459 2.27 7 3.08 8.56e-03

Raw data (tab-delimited .txt)