L2L Microarray Analysis Tool
Results for C01D.profile.u50
| Results summary | View all lists in L2L MDB | View all genes in C01D.profile.u50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| et743_blockstsa | Normally induced by the HDACi TSA, but induction is blocked by Et-743 | 15 | 0.04 | 3 | 80.91 | 6.72e-06 |
| uvc_high_all_dn | Down-regulated at any timepoint following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (clusters d1-d9) | 634 | 1.57 | 9 | 5.74 | 3.73e-05 |
| lvad_heartfailure_up | Upregulated in the left ventricle myocardium of patients with heart failure following implantation of a left ventricular assist device | 180 | 0.44 | 5 | 11.24 | 9.60e-05 |
| uvc_xpcs_8hr_up | Up-regulated at 8 hours following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC | 108 | 0.27 | 4 | 14.98 | 1.63e-04 |
| bay_pbmc_24hr_up | Up-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 202 | 0.50 | 5 | 10.01 | 1.64e-04 |
| uvc_xpcs_all_up | Up-regulated at any timepoint following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC | 112 | 0.28 | 4 | 14.45 | 1.87e-04 |
| hematop_stem_all_up | Up-regulated in populations of human hematopoietic stem cells (CD34+/CD38-/Lin-) from bone marrow, umbilical cord blood, and peripheral blood stem-progenitor cells, compared to the stem cell-depleted population (CD34+/[CD38/Lin++]) | 52 | 0.13 | 3 | 23.34 | 3.05e-04 |
| hypoxia_normal_up | Upregulated by hypoxia in normal, RPTEC renal cells (Fig. 3) | 376 | 0.93 | 6 | 6.46 | 3.95e-04 |
| aged_rhesus_up | Upregulated in the vastus lateralis muscle of aged vs. young adult rhesus monkeys | 390 | 0.96 | 6 | 6.22 | 4.79e-04 |
| uvc_high_d8_dn | Progressively down-regulated through 18 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d8) | 70 | 0.17 | 3 | 17.34 | 7.31e-04 |
| heat_glioblastoma_up | Up-regulated following 1 hr 43degC heat shock in human glioblastoma cells (U87MG). | 78 | 0.19 | 3 | 15.56 | 1.00e-03 |
| brca1_overexp_prostate_up | Up-regulated with stable, ectopic overexpression of BRCA1 in DU-145 human prostate cancer cell lines, compared to neo-only controls | 308 | 0.76 | 5 | 6.57 | 1.11e-03 |
| bay_pbmc_6hr_up | Up-regulated at 6 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 475 | 1.17 | 6 | 5.11 | 1.32e-03 |
| hdaci_colon_cur12hrs_up | Upregulated by curcumin at 12 hrs in SW260 colon carcinoma cells | 22 | 0.05 | 2 | 36.78 | 1.37e-03 |
| il2_pbmc_6hr_up | Up-regulated at 6hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 530 | 1.31 | 6 | 4.58 | 2.28e-03 |
| uvc_high_all_up | Up-regulated at any timepoint following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (clusters b1-b4) | 34 | 0.08 | 2 | 23.80 | 3.25e-03 |
| tsa_hepg2_dn | Down-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 500 nM trichostatin A (TSA). | 1237 | 3.06 | 9 | 2.94 | 4.24e-03 |
| uvc_ttd-xpcs_common_up | Up-regulated at any timepoint following treatment of both XPB/CS and XPB/TTD fibroblasts with 3 J/m^2 UVC | 44 | 0.11 | 2 | 18.39 | 5.40e-03 |
| prmt5_kd_dn | Down-regulated by stable RNAi knock-down of PRMT5 in NIH 3T3 cells | 45 | 0.11 | 2 | 17.98 | 5.64e-03 |
| il2_pbmc_24hr_dn | Down-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 646 | 1.60 | 6 | 3.76 | 5.91e-03 |
| hdaci_colon_but16hrs_up | Upregulated by butyrate at 16 hrs in SW260 colon carcinoma cells | 47 | 0.12 | 2 | 17.21 | 6.14e-03 |
| idx_tsa_up_cluster5 | Up-regulated at 48-96 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 5) | 149 | 0.37 | 3 | 8.15 | 6.24e-03 |
| heatshock_hela_4hr_dn | Down-regulated at 4 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05). | 1829 | 4.52 | 11 | 2.43 | 6.82e-03 |
| hdaci_colon_but12hrs_up | Upregulated by butyrate at 12 hrs in SW260 colon carcinoma cells | 54 | 0.13 | 2 | 14.98 | 8.03e-03 |
| vegf_huvec_2hrs_up | Up-regulated 2 hours after VEGF treatment in human umbilical vein endothelial cells | 54 | 0.13 | 2 | 14.98 | 8.03e-03 |